{"id":"W4366331504","doi":"10.7759/cureus.37784","title":"Eculizumab in the Treatment of Acetylcysteine-Induced Atypical Hemolytic Uremic Syndrome","year":2023,"lang":"en","type":"article","venue":"Cureus","topic":"Neonatal Health and Biochemistry","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Santé Montérégie; Centre Integre de Sante et de Services Sociaux de Laval; Université de Sherbrooke","funders":"","keywords":"Eculizumab; Atypical hemolytic uremic syndrome; Medicine; Acetylcysteine; Hemodialysis; Hemolysis; Complication; Pediatrics; Internal medicine; Complement system; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008773775,0.0000981472,0.0002170269,0.00003387351,0.00002274464,0.000002502668,0.0000910145,0.00009745884,0.00003636343],"category_scores_gemma":[0.00003765502,0.00005863651,0.00007155939,0.0003033832,0.00003055484,0.00001253191,0.00001187532,0.00008857837,0.00007538171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001336393,"about_ca_system_score_gemma":0.0001152296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000872256,"about_ca_topic_score_gemma":0.00002215266,"domain_scores_codex":[0.9992144,0.00001931868,0.0001984859,0.0001544994,0.0001854758,0.0002278073],"domain_scores_gemma":[0.9994844,0.00006434723,0.00003417699,0.0003110869,0.00001945382,0.00008649362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.009437371,0.01165703,0.05906188,0.008581071,0.0006749382,0.02587625,0.01633852,0.00001203628,0.7102097,0.001375281,0.02498928,0.1317866],"study_design_scores_gemma":[0.03348807,0.0203906,0.4864353,0.001785332,0.0005112363,0.01072599,0.006287498,0.001022051,0.3972864,0.0008830364,0.04019415,0.0009902837],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996263,0.0009733144,4.234973e-7,0.001586963,0.00008846166,0.0003560573,0.000008953845,0.00003553222,0.0006872435],"genre_scores_gemma":[0.9989452,0.0002104182,0.00002234034,0.000173566,0.00007608954,0.00003441836,0.00005092128,0.000008685588,0.0004783981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4273734,"threshold_uncertainty_score":0.2391127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04499534603352995,"score_gpt":0.3401825798969839,"score_spread":0.295187233863454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}