{"id":"W4366332482","doi":"10.1007/s41030-023-00222-2","title":"Results From a Phase 4, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Repository Corticotropin Injection for the Treatment of Pulmonary Sarcoidosis","year":2023,"lang":"en","type":"article","venue":"Pulmonary Therapy","topic":"Sarcoidosis and Beryllium Toxicity Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals","keywords":"Placebo; Medicine; Adverse effect; Discontinuation; Sarcoidosis; Internal medicine; Clinical trial; Pulmonary function testing; Randomized controlled trial; Glucocorticoid; Surgery; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004958411,0.001322816,0.003601683,0.0003738076,0.0005821105,0.0008485257,0.0006821807,0.001456408,0.003922596],"category_scores_gemma":[0.003671197,0.0005702769,0.001526481,0.0003784266,0.001172662,0.0008470281,0.0002434268,0.002081082,0.0004715493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003553114,"about_ca_system_score_gemma":0.001214336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003470496,"about_ca_topic_score_gemma":0.000836956,"domain_scores_codex":[0.9979876,0.001206569,0.0002304472,0.0002191289,0.0001797227,0.0001764812],"domain_scores_gemma":[0.9973781,0.00124306,0.0005082352,0.0001916082,0.0002365775,0.000442396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9511582,0.01179868,0.001051405,0.001027289,0.001272502,0.0000884711,0.00008432323,0.0003299415,0.01490689,0.00008325164,0.0006059074,0.01759304],"study_design_scores_gemma":[0.8357315,0.1555524,0.004925302,0.00004905707,0.00121512,0.00005807964,0.00002284784,0.0002009813,0.001578538,0.00007094227,0.0005768191,0.00001841543],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818181,0.006014757,0.001500237,0.0005575572,0.0004694998,0.006522074,0.00110255,0.0001526729,0.00186261],"genre_scores_gemma":[0.985979,0.00308273,0.002513754,0.0007818252,0.0004095301,0.004845636,0.001119947,0.00003411483,0.001233412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004958411,"threshold_uncertainty_score":0.02622288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08144340275263581,"score_gpt":0.3707308563317506,"score_spread":0.2892874535791148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}