{"id":"W4366332482","doi":"10.1007/s41030-023-00222-2","title":"Results From a Phase 4, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Repository Corticotropin Injection for the Treatment of Pulmonary Sarcoidosis","year":2023,"lang":"en","type":"article","venue":"Pulmonary Therapy","topic":"Sarcoidosis and Beryllium Toxicity Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals","keywords":"Placebo; Medicine; Adverse effect; Discontinuation; Sarcoidosis; Internal medicine; Clinical trial; Pulmonary function testing; Randomized controlled trial; Glucocorticoid; Surgery; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007805977,0.000333358,0.001553246,0.0003529509,0.00022691,0.00002654439,0.0002265434,0.0001304863,0.00003209779],"category_scores_gemma":[0.0001346594,0.0001905772,0.0007869487,0.0005599895,0.0002195624,0.00008337974,0.00003325333,0.0001501377,0.000005904372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001122494,"about_ca_system_score_gemma":0.0001054947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003398666,"about_ca_topic_score_gemma":0.00003224842,"domain_scores_codex":[0.9964731,0.0004979183,0.001366811,0.0005588643,0.0007134645,0.0003898105],"domain_scores_gemma":[0.9944985,0.003680019,0.0005497776,0.0008351201,0.0003124559,0.0001241615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8500662,0.02108042,0.00215747,0.00003216815,0.002375086,0.0000691362,0.002634823,0.0001261223,0.07521269,0.000002442875,0.00006066143,0.04618272],"study_design_scores_gemma":[0.9147015,0.008575167,0.002426761,0.00007521726,0.0008024587,0.00001842677,0.00281985,0.04378744,0.02623772,0.00002231636,0.0003721997,0.0001610072],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980077,0.003432484,0.00004702967,0.0006103567,0.0003582725,0.0150162,0.000143322,0.00008141628,0.0002339691],"genre_scores_gemma":[0.9869519,0.007143154,0.00004559593,0.00003408858,0.0003972379,0.0038523,0.000207307,0.00005299003,0.001315374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06463518,"threshold_uncertainty_score":0.7771513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08144340275263581,"score_gpt":0.3707308563317506,"score_spread":0.2892874535791148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}