{"id":"W4366416036","doi":"10.51731/cjht.2023.622","title":"Dupilumab (Dupixent)","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reimbursement; Dupilumab; Medicine; Asthma; Family medicine; Intensive care medicine; Immunology; Health care; Political science","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006732399,0.000458293,0.0003884699,0.001103244,0.0004748409,0.001135291,0.0005746046,0.0008154985,0.03941222],"category_scores_gemma":[0.001021904,0.0001187002,0.0005633595,0.0005964598,0.0003448555,0.0005961046,0.0004826445,0.0009790168,0.01046131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001810878,"about_ca_system_score_gemma":0.002571716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02265524,"about_ca_topic_score_gemma":0.0657912,"domain_scores_codex":[0.999585,0.00007075677,0.00003044319,0.00006367407,0.00019367,0.00005656359],"domain_scores_gemma":[0.9995033,0.00008840078,0.00008634566,0.00001655143,0.0002057551,0.00009959406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004604446,0.00007549692,0.0004349436,0.003100564,0.00005990409,0.0001869734,0.00005537994,0.00008333573,0.003421739,0.003186383,0.2261486,0.7627863],"study_design_scores_gemma":[0.000173554,0.0003218285,0.001695628,0.0009946078,0.00007069574,0.0006262071,0.00002499215,0.0000666477,0.002034143,0.0002456995,0.993733,0.00001294584],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01051036,0.6151329,0.002716347,0.01413756,0.004207213,0.0005956232,0.00787347,0.0009185701,0.343908],"genre_scores_gemma":[0.146792,0.4640609,0.009981102,0.02656681,0.002548653,0.0005670246,0.01229393,0.0001862655,0.3370032],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03941222,"threshold_uncertainty_score":0.131847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1235445147820354,"score_gpt":0.4074486576882895,"score_spread":0.2839041429062541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}