{"id":"W4366423259","doi":"10.1002/dad2.12417","title":"Generalizability of cognitive results from clinical trial participants to an older adult population: Addressing external validity","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; National Center for Complementary and Integrative Health; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; National Institute on Aging; Alzheimer's Association","keywords":"Generalizability theory; Randomized controlled trial; External validity; Population; Psychology; Cognition; Cohort; Clinical psychology; Depression (economics); Medicine; Psychiatry; Developmental psychology; Internal medicine; Social psychology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.6528168,0.001285533,0.003159001,0.003790319,0.001569905,0.00496849,0.003282752,0.002238849,0.003756716],"category_scores_gemma":[0.802343,0.001152533,0.005622496,0.004736477,0.007816873,0.004445606,0.004701669,0.002959851,0.0005702657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004720354,"about_ca_system_score_gemma":0.007221587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002743846,"about_ca_topic_score_gemma":0.00230402,"domain_scores_codex":[0.3567236,0.4812471,0.09542142,0.01954344,0.04533511,0.001729443],"domain_scores_gemma":[0.1179081,0.7412691,0.06018215,0.05814759,0.02173348,0.0007596401],"domain_codex":"methods","domain_gemma":"methods","domain_candidate":"methods","domain_consensus":"methods","study_design_codex":"observational","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.006662871,0.0007840282,0.4120496,0.05904942,0.03850292,0.000703047,0.02297599,0.008227401,0.002217811,0.05731557,0.01684857,0.3746628],"study_design_scores_gemma":[0.006243205,0.009585014,0.5643221,0.05185703,0.02658582,0.001840614,0.005971833,0.04102074,0.01006246,0.1981468,0.08366068,0.0007038348],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.2567942,0.06051086,0.5468713,0.02750783,0.00540986,0.06036556,0.005440466,0.001020771,0.03607905],"genre_scores_gemma":[0.8770475,0.002973188,0.06728625,0.007586547,0.0009678139,0.04142525,0.00115598,0.0002690605,0.001288347],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.3471832,"threshold_uncertainty_score":0.4281388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.298525284592911,"score_gpt":0.5088776280036136,"score_spread":0.2103523434107026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}