{"id":"W4366427883","doi":"10.22541/au.168187871.14331560/v1","title":"Autoreactive IgE: pathogenic role and therapeutic target in autoimmune diseases","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Urticaria and Related Conditions","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Fonds Wetenschappelijk Onderzoek; Fondation pour la Recherche Médicale; Agence Nationale de la Recherche; Laboratoire d'Excellence Inflamex","keywords":"Immunology; Immunoglobulin E; Isotype; Autoantibody; Autoimmunity; Antibody; Biology; Antigen; Population; Medicine; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005338101,0.0003388945,0.0005406327,0.0004349857,0.0001345098,0.0009681747,0.0002414657,0.0008264802,0.002705383],"category_scores_gemma":[0.000413138,0.00008353076,0.0002174536,0.0003230778,0.0002749101,0.0005885799,0.0004197093,0.0008709768,0.001424392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002552083,"about_ca_system_score_gemma":0.0003473574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007638275,"about_ca_topic_score_gemma":0.0001000238,"domain_scores_codex":[0.9998223,0.00005197735,0.00001553124,0.00002465955,0.00006006463,0.00002554583],"domain_scores_gemma":[0.9998952,0.00004068328,0.00001637168,0.000007360269,0.00002355596,0.00001676026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0006116329,0.0002102739,0.001166318,0.009229227,0.0001131477,0.001559483,0.000293914,0.0004115805,0.06002258,0.01658767,0.02002229,0.8897719],"study_design_scores_gemma":[0.0001259194,0.0008999466,0.00434853,0.002262625,0.0002215672,0.007362845,0.0002256136,0.0004727363,0.0282275,0.0142711,0.9415522,0.0000294042],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.008768542,0.976232,0.001996386,0.002370217,0.001020587,0.00003199504,0.00008780394,0.00007772753,0.009414802],"genre_scores_gemma":[0.1006468,0.8805082,0.004413228,0.002061608,0.002564721,0.00007931895,0.0003146651,0.00004753755,0.009363793],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002705383,"threshold_uncertainty_score":0.009050429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0170073564851766,"score_gpt":0.2738234431079345,"score_spread":0.256816086622758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}