{"id":"W4366440791","doi":"10.4088/jcp.22m14739","title":"The Efficacy of Lumateperone in Patients With Bipolar Depression With Mixed Features","year":2023,"lang":"en","type":"article","venue":"The Journal of Clinical Psychiatry","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brain and Cognition Discovery Foundation; University of Toronto","funders":"","keywords":"Young Mania Rating Scale; Hypomania; Bipolar disorder; Mania; Psychology; Placebo; Internal medicine; Clinical Global Impression; Post-hoc analysis; Rating scale; Montgomery–Åsberg Depression Rating Scale; Bipolar I disorder; Bipolar II disorder; Psychiatry; Major depressive disorder; Medicine; Mood","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010027,0.0006128095,0.001703146,0.0003490216,0.0003288626,0.0005105562,0.0003445182,0.0004900848,0.003469826],"category_scores_gemma":[0.0009264832,0.0004001631,0.001179742,0.0003096177,0.0003092537,0.0003894744,0.000204448,0.0008980664,0.000342925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004882994,"about_ca_system_score_gemma":0.0005559571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006590682,"about_ca_topic_score_gemma":0.003805581,"domain_scores_codex":[0.9996483,0.0001927747,0.00003743472,0.00005366307,0.00002453924,0.0000432864],"domain_scores_gemma":[0.9995739,0.0001116792,0.0001350151,0.00003021073,0.00003172931,0.000117471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9106091,0.004999342,0.004909527,0.001660595,0.002834474,0.000145835,0.00008442382,0.0003068578,0.01168346,0.00009357974,0.0008946998,0.06177806],"study_design_scores_gemma":[0.750602,0.2070685,0.03582048,0.0001367578,0.002394118,0.000234977,0.00008111314,0.0007232876,0.001220556,0.0002050483,0.001480396,0.00003281902],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878091,0.007836891,0.0003596642,0.0003149097,0.0001496517,0.00111439,0.0006559456,0.00006102672,0.001698343],"genre_scores_gemma":[0.9952689,0.001952487,0.0006569695,0.0004421921,0.0001147244,0.0006186309,0.0004094508,0.000004713426,0.0005319885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003469826,"threshold_uncertainty_score":0.01160771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01835082122136117,"score_gpt":0.3353535840383948,"score_spread":0.3170027628170336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}