{"id":"W4366464017","doi":"10.1080/1040841x.2023.2197491","title":"Exploring halophilic environments as a source of new antibiotics","year":2023,"lang":"en","type":"article","venue":"Critical Reviews in Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University; University of East Anglia; Department for the Economy; Queen's University Belfast; Department for Employment and Learning, Northern Ireland","keywords":"Halophile; Bioprospecting; Biology; Isolation (microbiology); Metagenomics; Extreme environment; Haloarchaea; Organism; Biotechnology; Ecology; Bioinformatics; Bacteria; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003802057,0.0004438609,0.0006110307,0.0008763052,0.0002487442,0.001111803,0.0003750355,0.00078791,0.001589225],"category_scores_gemma":[0.000338579,0.0001973178,0.0004502381,0.0006006798,0.0004065838,0.0009974488,0.0006914423,0.0009596838,0.000770889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004040936,"about_ca_system_score_gemma":0.000596418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003155674,"about_ca_topic_score_gemma":0.0008410356,"domain_scores_codex":[0.9997091,0.00007207559,0.00001963208,0.00005039683,0.000105656,0.00004310319],"domain_scores_gemma":[0.9998485,0.00005151522,0.00003349615,0.000009555411,0.00003705745,0.00001982813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002741293,0.0001404498,0.001931857,0.01570951,0.0001893877,0.001266189,0.000433833,0.001676394,0.4736996,0.01767858,0.009460291,0.4775398],"study_design_scores_gemma":[0.00002509448,0.0007582292,0.005958233,0.002623539,0.0002720851,0.002473563,0.0005537117,0.001254427,0.1864042,0.009579728,0.7900207,0.00007656396],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02495935,0.9535857,0.008878369,0.002110529,0.0005314495,0.00004038914,0.0001996847,0.00008569941,0.009608782],"genre_scores_gemma":[0.0977044,0.8880334,0.008617396,0.001038534,0.0004858305,0.00003855306,0.0002251485,0.0000247254,0.003831956],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001589225,"threshold_uncertainty_score":0.005316556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1327989793875434,"score_gpt":0.3402252639816548,"score_spread":0.2074262845941114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}