{"id":"W4366520880","doi":"10.1016/j.stemcr.2023.03.013","title":"IRX5 promotes DNA damage repair and activation of hair follicle stem cells","year":2023,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Biology; Hair follicle; Stem cell; DNA damage; Cell biology; DNA repair; DNA; Andrology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003633866,0.000131087,0.0002727892,0.0001352345,0.00005553557,0.000009731491,0.00002739315,0.00009248962,0.00002399299],"category_scores_gemma":[0.00001962943,0.0001152376,0.00009760103,0.000369284,0.00004920944,0.00009773178,0.0000456153,0.00008464827,0.00001580989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002172103,"about_ca_system_score_gemma":0.0001035405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005289645,"about_ca_topic_score_gemma":0.000005671688,"domain_scores_codex":[0.9986986,0.00003057825,0.0004258897,0.0003288829,0.0002885162,0.0002275117],"domain_scores_gemma":[0.9990842,0.00006048129,0.0002212939,0.0004104453,0.00007899455,0.000144638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001796965,0.0003664852,0.1533778,0.002778304,0.0001081414,0.001961403,0.003415508,0.00002732325,0.8124938,0.00007066086,0.0131111,0.01210982],"study_design_scores_gemma":[0.0007933978,0.0003405051,0.03134953,0.0001883669,0.00007047629,0.00007609217,0.002362508,0.0004936879,0.9576239,0.0001289991,0.006384064,0.0001884713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850601,0.00009964264,0.0000280556,0.0001532898,0.0001374399,0.0005542067,0.000002558376,0.0002941758,0.01367052],"genre_scores_gemma":[0.9910523,0.00002127267,0.00009093885,0.00005063808,0.00003479818,0.00001735971,0.00001618621,0.00002674728,0.00868972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1451301,"threshold_uncertainty_score":0.4699253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01460614984560254,"score_gpt":0.2377634727624503,"score_spread":0.2231573229168478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}