{"id":"W4366599450","doi":"10.3390/curroncol30040323","title":"Metastatic Castration-Resistant Prostate Cancer, Immune Checkpoint Inhibitors, and Beyond","year":2023,"lang":"en","type":"review","venue":"Current Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Prostate cancer; Medicine; Pembrolizumab; Immunotherapy; Immune checkpoint; Cancer; PARP inhibitor; Oncology; Ipilimumab; Cancer research; Internal medicine; Poly ADP ribose polymerase; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006011977,0.0004789828,0.00221411,0.0003073397,0.0001066087,0.00003370043,0.0001166538,0.0002258109,0.0001433516],"category_scores_gemma":[0.00007372314,0.0003590543,0.0005168439,0.0005080869,0.0002644546,0.00005017008,0.00009171354,0.0006229641,0.00004631492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000773199,"about_ca_system_score_gemma":0.00208092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001527031,"about_ca_topic_score_gemma":0.0001960991,"domain_scores_codex":[0.997249,0.0002056185,0.001326067,0.0005550415,0.0002450347,0.0004192312],"domain_scores_gemma":[0.9984893,0.0002037389,0.0007112151,0.0003313005,0.000104026,0.0001603737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003032097,0.0001814587,0.000006110602,0.02917463,0.000731958,0.00009072549,0.0002256326,3.82627e-8,0.00008839326,0.00002328639,0.002896438,0.9662781],"study_design_scores_gemma":[0.001858012,0.0006588622,0.00005115126,0.01289896,0.002359149,0.0001823271,0.0001094031,0.000002841188,0.0000141486,0.00003417674,0.9815171,0.0003138139],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001691751,0.9936354,0.000001487287,0.0004434638,0.003023469,0.002138993,0.0003019977,0.00008628598,0.0001997982],"genre_scores_gemma":[0.0000116519,0.9970115,0.00007472275,0.00003633199,0.0004423436,0.00090189,0.0005754674,0.00008165559,0.0008644034],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9786207,"threshold_uncertainty_score":0.9998862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1533171886036247,"score_gpt":0.4500440351909837,"score_spread":0.296726846587359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}