{"id":"W4366602099","doi":"10.1002/etc.5638","title":"Effects of Alkylation on Potency of Benz[a]anthracene for AhR2 Transactivation in Nine Species of Freshwater Fish","year":2023,"lang":"en","type":"article","venue":"Environmental Toxicology and Chemistry","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; University of California, Davis; Oregon State University; University of Lethbridge; Alberta Conservation Association","keywords":"Alkylation; Chemistry; Potency; Transactivation; Anthracene; Environmental chemistry; Stereochemistry; In vitro; Organic chemistry; Biochemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003066273,0.0003141224,0.000232362,0.0004480855,0.0003531604,0.0002646354,0.0002030698,0.0004410511,0.0007948993],"category_scores_gemma":[0.0004903048,0.0002615918,0.000473032,0.0002598361,0.0004486726,0.0003537851,0.0003638515,0.0003783859,0.0001935547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005504552,"about_ca_system_score_gemma":0.0002804029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003398848,"about_ca_topic_score_gemma":0.01348929,"domain_scores_codex":[0.9996245,0.00005597734,0.0000588288,0.0001222237,0.00009122078,0.00004708234],"domain_scores_gemma":[0.9994377,0.0001430104,0.0001727407,0.00003426876,0.0001336373,0.00007852698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001896639,0.00003090034,0.003478462,0.00003321822,0.00001854633,0.00003481256,0.00007803748,0.0001181632,0.9952661,0.00001020896,0.000008074615,0.0007338075],"study_design_scores_gemma":[0.00002691724,0.006853077,0.2662562,0.00001625891,0.0002232589,0.000352129,0.0004936848,0.0009987323,0.723169,0.00005785351,0.00150404,0.00004884501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990637,0.0001438092,0.0002630646,0.00001723752,0.000005521993,0.00001710791,0.0001460017,0.000006433467,0.0003371921],"genre_scores_gemma":[0.9952682,0.000422237,0.002053723,0.0000747212,0.000005487946,0.0000451472,0.0006018008,0.00001132571,0.001517381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003398848,"threshold_uncertainty_score":0.006758094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005304584078794789,"score_gpt":0.2029699985882456,"score_spread":0.1976654145094508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}