{"id":"W4366603326","doi":"10.1177/00220345231162336","title":"Mechanistic Insights into Bioengineered Antibiofilm Enamel Pellicles","year":2023,"lang":"en","type":"article","venue":"Journal of Dental Research","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alliance de recherche numérique du Canada","keywords":"Biofilm; Enamel paint; Chemistry; Amelogenin; Biophysics; Circular dichroism; Bioburden; In silico; Pentapeptide repeat; Proteome; Biochemistry; Amphiphile; Bacteria; Peptide; Computational biology; Microbiology; Biology; Polymer; Materials science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007309549,0.0001058584,0.0002407278,0.0006170426,0.0002530503,0.00004977566,0.0003391601,0.0001379437,0.0003653503],"category_scores_gemma":[0.0002040107,0.00008164978,0.0001336755,0.0004576065,0.0002605238,0.0001684781,0.0001733439,0.0006423823,0.002149896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000605046,"about_ca_system_score_gemma":0.00009169785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006787374,"about_ca_topic_score_gemma":0.00001439571,"domain_scores_codex":[0.9988034,0.0001997621,0.0003086803,0.0001329123,0.0001570302,0.0003982084],"domain_scores_gemma":[0.999218,0.0003024236,0.00009745257,0.0001275885,0.0002075363,0.00004693605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001236759,0.00007982703,0.0003140309,0.00002892657,0.00009821366,0.0001536889,0.000351844,0.000008393127,0.9664481,0.000861341,0.02860083,0.002931077],"study_design_scores_gemma":[0.001041074,0.00082807,0.003696189,0.0001788616,0.00002137272,0.0004666664,0.004643314,0.00004799952,0.9650283,0.003764305,0.02010183,0.0001819701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967873,0.001688079,0.00009474598,0.0002301456,0.0005964251,0.00008105452,0.000006544605,0.00002534168,0.0004903276],"genre_scores_gemma":[0.9937468,0.001345119,0.0000859299,0.0000225359,0.0001268067,8.339467e-7,0.00001402896,0.00001708496,0.004640864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008498996,"threshold_uncertainty_score":0.9986271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0459280151493335,"score_gpt":0.337372244129605,"score_spread":0.2914442289802715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}