{"id":"W4366609028","doi":"10.1016/j.mcpro.2023.100556","title":"Germ Cell–Specific Proteins AKAP4 and ASPX Facilitate Identification of Rare Spermatozoa in Non-Obstructive Azoospermia","year":2023,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Toronto; Sunnybrook Hospital; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Sunnybrook Health Science Centre; CReATe Fertility Centre","funders":"Canadian Institutes of Health Research; Physicians' Services Incorporated Foundation; University of Alberta; Prostate Cancer Canada; Movember Foundation","keywords":"Azoospermia; Identification (biology); Germ cell; Chemistry; Andrology; Medicine; Computational biology; Biology; Biochemistry; Genetics; Infertility; Pregnancy; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004632294,0.0002849473,0.0004442082,0.0004010654,0.00007332216,0.00004136893,0.0001234405,0.0002141773,0.00003155209],"category_scores_gemma":[0.0001362026,0.0002900244,0.0001458376,0.0007766503,0.0001568662,0.0001311341,0.00009597661,0.0003238705,0.0001148007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001180353,"about_ca_system_score_gemma":0.00009022178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006429829,"about_ca_topic_score_gemma":0.000002743426,"domain_scores_codex":[0.9978701,0.00009627586,0.0006554804,0.0005819776,0.0004283231,0.0003677709],"domain_scores_gemma":[0.9988311,0.00002942959,0.000236593,0.0005855452,0.0001793558,0.0001380013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001136544,0.0001075964,0.007572638,0.0004158636,0.00003360065,0.0005713115,0.0008366727,0.0001470496,0.9888058,0.0001709158,0.00005943481,0.001165505],"study_design_scores_gemma":[0.001589476,0.0001444461,0.04876712,0.0001207082,0.00005915152,0.00007456265,0.0003537314,0.003815027,0.9438949,0.0006460469,0.0002769094,0.0002578686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861687,0.0006201888,0.009796593,0.0001606591,0.0001464183,0.002584616,0.00003151856,0.00009393732,0.0003973503],"genre_scores_gemma":[0.9964309,0.0001287796,0.002425171,0.00003214695,0.0000448018,0.0001993223,0.0002178449,0.00006213878,0.0004589256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04491081,"threshold_uncertainty_score":0.9999552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190003111966549,"score_gpt":0.2187721337750076,"score_spread":0.2068721026553421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}