{"id":"W4366609028","doi":"10.1016/j.mcpro.2023.100556","title":"Germ Cell–Specific Proteins AKAP4 and ASPX Facilitate Identification of Rare Spermatozoa in Non-Obstructive Azoospermia","year":2023,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Toronto; Sunnybrook Hospital; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Sunnybrook Health Science Centre; CReATe Fertility Centre","funders":"Canadian Institutes of Health Research; Physicians' Services Incorporated Foundation; University of Alberta; Prostate Cancer Canada; Movember Foundation","keywords":"Azoospermia; Identification (biology); Germ cell; Chemistry; Andrology; Medicine; Computational biology; Biology; Biochemistry; Genetics; Infertility; Pregnancy; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005227482,0.0003953699,0.0002843761,0.001429791,0.0002537254,0.0005678488,0.0002833745,0.0004724737,0.001264161],"category_scores_gemma":[0.0004673809,0.0001754716,0.0003373263,0.0005541256,0.0002703021,0.0002714723,0.0004081069,0.0003865029,0.0003410966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001893384,"about_ca_system_score_gemma":0.0001904062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005574732,"about_ca_topic_score_gemma":0.0007363973,"domain_scores_codex":[0.999779,0.00003473619,0.00002516949,0.00006196087,0.00007060103,0.00002859859],"domain_scores_gemma":[0.9997922,0.0000512657,0.00005901507,0.0000167759,0.00004681902,0.00003395061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003697978,0.00003882183,0.04068644,0.0002506959,0.00006477852,0.0004670494,0.00008261203,0.000168381,0.940118,0.0001670232,0.0002004957,0.01738596],"study_design_scores_gemma":[0.00003412701,0.0006755152,0.3963666,0.00005604449,0.0001979709,0.004946183,0.0002323222,0.004815058,0.5855058,0.0004915249,0.006650065,0.00002877811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98258,0.004968387,0.01020393,0.0001626465,0.00003975751,0.00006447406,0.0008528563,0.0001962467,0.0009317609],"genre_scores_gemma":[0.9858559,0.001619977,0.01041802,0.00009462942,0.00002553042,0.0000344421,0.0008106981,0.0000197626,0.001120912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001429791,"threshold_uncertainty_score":0.004229009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190003111966549,"score_gpt":0.2187721337750076,"score_spread":0.2068721026553421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}