{"id":"W4366742407","doi":"10.1111/pcmr.13091","title":"<scp>B7‐H3</scp> drives immunosuppression and Co‐targeting with <scp>CD47</scp> is a new therapeutic strategy in β‐catenin activated melanomas","year":2023,"lang":"en","type":"article","venue":"Pigment Cell & Melanoma Research","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; National Cancer Institute; Melanoma Research Alliance","keywords":"Tumor microenvironment; Immunotherapy; Cancer research; Immune checkpoint; CD47; Melanoma; Cancer immunotherapy; Immune system; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001083611,0.000193299,0.0002037869,0.000151563,0.0001406966,0.0002626407,0.0001560551,0.0002119229,0.001298283],"category_scores_gemma":[0.00004034169,0.00008671768,0.0001563385,0.0001068237,0.0002418202,0.0001132758,0.0001314838,0.0006816335,0.0003626193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002542635,"about_ca_system_score_gemma":0.0002529511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007935358,"about_ca_topic_score_gemma":0.001407133,"domain_scores_codex":[0.9998615,0.00001636019,0.000008234111,0.0000222229,0.00005332156,0.0000384285],"domain_scores_gemma":[0.9999516,0.000006748079,0.00001210476,0.000006192822,0.000005308826,0.00001789821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006160197,0.00002602627,0.00005104811,0.00001230403,0.000002423525,0.00001409158,0.000003559064,0.00006039735,0.9990277,0.00008525128,0.00004982808,0.0006057799],"study_design_scores_gemma":[0.000009481355,0.00016739,0.0006566841,0.0000016804,0.000005655871,0.00004811499,0.000008136148,0.0006044813,0.9973188,0.00001779498,0.001160319,0.000001336629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947333,0.0009270178,0.001968011,0.0001613469,0.00003116728,0.00002865919,0.0001945246,0.00008313653,0.001872745],"genre_scores_gemma":[0.9958333,0.0003707393,0.001490642,0.00005428406,0.00000927756,0.00002920563,0.0001975855,0.00001765003,0.001997281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001298283,"threshold_uncertainty_score":0.004343152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04549630480020137,"score_gpt":0.3176609703955188,"score_spread":0.2721646655953174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}