{"id":"W4366742756","doi":"10.1503/cjs.005822","title":"Total neoadjuvant therapy for rectal cancer: a guide for surgeons","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Surgery","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba; University of British Columbia","funders":"","keywords":"Medicine; Colorectal cancer; Regimen; Neoadjuvant therapy; Radiation therapy; Systemic therapy; Randomized controlled trial; Chemotherapy; General surgery; Oncology; Surgery; Medical physics; Cancer; Internal medicine; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006895845,0.000167856,0.0006327733,0.0005867389,0.0001383276,0.00002953751,0.00007472943,0.00009351765,0.0002425453],"category_scores_gemma":[0.0006406278,0.0001390373,0.0006999786,0.0004718324,0.00006187539,0.00008978141,0.000005124593,0.0001256136,0.000005905592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005268407,"about_ca_system_score_gemma":0.00499787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005124566,"about_ca_topic_score_gemma":0.009528038,"domain_scores_codex":[0.9984654,0.00002731363,0.0005433298,0.000178105,0.0001916393,0.0005941906],"domain_scores_gemma":[0.9971622,0.001095094,0.0002083738,0.0001403739,0.0004435452,0.0009503871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002243346,0.00006277067,0.2744218,0.0001014606,0.0008091608,0.001746705,0.0002919043,0.00005479093,0.000652143,0.0000414576,0.4681638,0.2514106],"study_design_scores_gemma":[0.003458956,0.0007750972,0.2875477,0.0004528938,0.0001540667,0.000781088,0.0001624946,0.0001321891,0.001459661,0.0002505492,0.7045323,0.0002930985],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873682,0.002997949,0.00003730403,0.005641177,0.002607197,0.0006177049,0.000356234,0.00002653046,0.00034774],"genre_scores_gemma":[0.9945682,0.0008712932,0.0001786407,0.000527062,0.0007488234,0.0001916184,0.00005364095,0.00006050598,0.002800217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2511175,"threshold_uncertainty_score":0.8866007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09019736577448209,"score_gpt":0.3383876250200936,"score_spread":0.2481902592456115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}