{"id":"W4366754148","doi":"10.1016/j.bbih.2023.100628","title":"Sex-specific effects of voluntary wheel running on behavior and the gut microbiota-immune-brain axis in mice","year":2023,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; McGill University; Douglas Mental Health University Institute; Carleton University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Anxiety; Gut–brain axis; Gut flora; Wheel running; Open field; Immune system; Turnover; Depression (economics); Elevated plus maze; Physiology; Hippocampus; Medicine; Mental health; Internal medicine; Psychology; Immunology; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004505989,0.0009179894,0.0006686845,0.001529045,0.0004910436,0.0006147189,0.0004896356,0.0009093517,0.003489998],"category_scores_gemma":[0.0002309619,0.000583107,0.0009517428,0.0003923076,0.0007159768,0.000502834,0.0005514383,0.002060398,0.0007212823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004799357,"about_ca_system_score_gemma":0.0005020933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001160964,"about_ca_topic_score_gemma":0.002488612,"domain_scores_codex":[0.99926,0.00007767718,0.0000697238,0.000274453,0.0001216437,0.0001964894],"domain_scores_gemma":[0.9994012,0.00004339344,0.0001876665,0.00007653953,0.00006693849,0.0002243075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003721489,0.001642139,0.002723539,0.000129902,0.00005657661,0.0002115545,0.0002304972,0.0001464839,0.984628,0.0002985374,0.0003557588,0.005855627],"study_design_scores_gemma":[0.0009165402,0.0144997,0.1249052,0.0001901722,0.0004843589,0.0008482004,0.0007198632,0.003551393,0.8410963,0.001051319,0.01157227,0.0001645832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882858,0.001733692,0.003820083,0.0003749609,0.0002270118,0.000183735,0.0031079,0.0003407352,0.001925978],"genre_scores_gemma":[0.9603713,0.002786116,0.007516754,0.0008777017,0.0001076134,0.001459108,0.00406405,0.0003210014,0.02249644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003489998,"threshold_uncertainty_score":0.01167524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02973349030373946,"score_gpt":0.2976043231349766,"score_spread":0.2678708328312371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}