{"id":"W4366817096","doi":"10.1093/nar/gkad306","title":"Depositing centromere repeats induces heritable intragenic heterochromatin establishment and spreading in <i>Arabidopsis</i>","year":2023,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Plant Molecular Biology Research","field":"Agricultural and Biological Sciences","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McMaster Institute for Research on Aging, McMaster University; National Institutes of Health; National Institute of General Medical Sciences; Northwestern University","keywords":"Biology; Heterochromatin; Genetics; DNA methylation; Epigenetics; Epigenome; Locus (genetics); Arabidopsis; Flowering Locus C; Histone; DNA demethylation; Euchromatin; Gene; Chromosome; Mutant","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001105282,0.0002577397,0.0001167219,0.0001517861,0.000115615,0.0001985509,0.0002463298,0.0001725128,0.0007716251],"category_scores_gemma":[0.00008610791,0.0001939753,0.0001608421,0.00007784979,0.0001706802,0.0001255933,0.0002574079,0.0004235713,0.0002653565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002974059,"about_ca_system_score_gemma":0.0001614263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007632385,"about_ca_topic_score_gemma":0.00167972,"domain_scores_codex":[0.9998943,0.00001030448,0.000009649412,0.00003962924,0.00002551387,0.00002058117],"domain_scores_gemma":[0.9998747,0.00001611183,0.00004567616,0.00002605571,0.000008444954,0.0000290409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001040843,0.000003742053,0.0000532147,0.000005972409,0.000001185279,0.00001551316,0.000003650185,0.00001739068,0.9995102,0.0000366685,0.000005644456,0.000336372],"study_design_scores_gemma":[0.000005130279,0.00006745287,0.003572634,0.000002121901,0.000006409761,0.0001175407,0.00001081602,0.0006646879,0.9944336,0.00003637002,0.001079619,0.000003694588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900738,0.0003387356,0.007202919,0.0000442676,0.00001994114,0.00003199164,0.0001783035,0.0002888284,0.001821286],"genre_scores_gemma":[0.9949679,0.0001616393,0.002553833,0.00003172765,0.000004854469,0.00001588368,0.0002440401,0.00006297989,0.001957193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007716251,"threshold_uncertainty_score":0.002581298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04623010532316899,"score_gpt":0.3009192545178963,"score_spread":0.2546891491947273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}