{"id":"W4366817657","doi":"10.1016/j.ultrasmedbio.2023.02.017","title":"Current and Emerging Systems for Focused Ultrasound-Mediated Blood–Brain Barrier Opening","year":2023,"lang":"en","type":"review","venue":"Ultrasound in Medicine & Biology","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kingston Health Sciences Centre; Queen's University","funders":"","keywords":"Blood–brain barrier; Focused ultrasound; Medicine; Clinical trial; Variety (cybernetics); Neuroscience; Intensive care medicine; Medical physics; Computer science; Ultrasound; Pathology; Central nervous system; Psychology; Radiology; Internal medicine; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007155133,0.001021451,0.001176667,0.001696717,0.0003370286,0.001269069,0.001109801,0.00128796,0.00374394],"category_scores_gemma":[0.0006554627,0.0004476511,0.0006455978,0.00137078,0.0005874733,0.001693778,0.000787786,0.001552793,0.002217161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005153755,"about_ca_system_score_gemma":0.0008075401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006961361,"about_ca_topic_score_gemma":0.001101935,"domain_scores_codex":[0.9997908,0.00002602634,0.00002135517,0.00004894396,0.00008070125,0.00003215546],"domain_scores_gemma":[0.9997157,0.0001485438,0.00005073511,0.00001087395,0.0000541118,0.00001996874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001169404,0.0001699757,0.0001657291,0.02048388,0.00008609959,0.0001908015,0.00007951528,0.00056813,0.02596801,0.008820249,0.01166898,0.9316818],"study_design_scores_gemma":[0.0000329392,0.0004248881,0.0007953629,0.002507629,0.0002016513,0.001170421,0.00009032072,0.0004905941,0.0169768,0.003464869,0.9737932,0.00005135876],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005135266,0.9953817,0.001336395,0.0002185376,0.0001831688,0.00001793826,0.00002806719,0.00002136249,0.002299318],"genre_scores_gemma":[0.002851537,0.9939574,0.001312607,0.000187516,0.0001458414,0.00003429123,0.00005136958,0.000004720801,0.001454755],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00374394,"threshold_uncertainty_score":0.01252472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04561732740214735,"score_gpt":0.3370486574042302,"score_spread":0.2914313300020829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}