{"id":"W4366818270","doi":"10.1002/cpz1.737","title":"The Robogut: A Bioreactor Model of the Human Colon for Evaluation of Gut Microbial Community Ecology and Function","year":2023,"lang":"en","type":"article","venue":"Current Protocols","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Breakthrough T1D Canada; Canadian Institutes of Health Research; Canada Foundation for Innovation; Canada Research Chairs","keywords":"Protocol (science); Bioreactor; Microbiome; Biochemical engineering; Microbial population biology; Biology; Microbial ecology; Function (biology); Biotechnology; Computer science; Ecology; Bioinformatics; Bacteria; Medicine; Pathology; Engineering; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001247461,0.0008791588,0.0005944366,0.0009185247,0.0006597514,0.0008742531,0.001136108,0.001462388,0.004068217],"category_scores_gemma":[0.0006371937,0.0004974835,0.001029705,0.0006251584,0.0006091195,0.0006606738,0.001031351,0.001525283,0.001503565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000778859,"about_ca_system_score_gemma":0.001769441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005352095,"about_ca_topic_score_gemma":0.007659554,"domain_scores_codex":[0.9989735,0.0002745447,0.00006328544,0.0002233114,0.0003486125,0.0001168277],"domain_scores_gemma":[0.9994604,0.0001192733,0.00009281514,0.0001157419,0.0000963782,0.0001153588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001339771,0.0003500767,0.001243244,0.0004637155,0.00003287213,0.0005004097,0.0001530166,0.002272679,0.978242,0.001569834,0.002430381,0.011402],"study_design_scores_gemma":[0.0004975772,0.009562197,0.01742157,0.0004378367,0.0002684778,0.002440028,0.0004164707,0.03861102,0.8275764,0.001578198,0.1009457,0.0002445465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5627045,0.01076558,0.3718787,0.001732722,0.001137011,0.00440674,0.01935829,0.003994702,0.02402181],"genre_scores_gemma":[0.5892375,0.006282229,0.368086,0.0007714363,0.00007353179,0.0065372,0.0106925,0.0004528868,0.0178667],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.005352095,"threshold_uncertainty_score":0.01360959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1385848397593592,"score_gpt":0.4189263645145646,"score_spread":0.2803415247552054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}