{"id":"W4367040516","doi":"10.1007/s12311-023-01558-w","title":"Natural History of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay: a 4-Year Longitudinal Study","year":2023,"lang":"en","type":"article","venue":"The Cerebellum","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke; Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean; McGill University; Centre for Interdisciplinary Research in Rehabilitation; Montreal Neurological Institute and Hospital; Université Laval","funders":"","keywords":"Balance (ability); Physical medicine and rehabilitation; Natural history study; Medicine; Population; Cohort; Natural history; Spastic; Physical therapy; Preferred walking speed; Ataxia; Longitudinal study; Cohort study; Rehabilitation; Cerebral palsy; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001906157,0.0001991125,0.0002943853,0.0001438691,0.00008962968,0.000009909601,0.0006612728,0.00003018101,0.0001850499],"category_scores_gemma":[0.0007818647,0.0001478204,0.0001157669,0.0005217068,0.0004750818,0.0000761252,0.0003050668,0.0001900897,0.0001625967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007424834,"about_ca_system_score_gemma":0.0001742996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008572091,"about_ca_topic_score_gemma":0.00005467026,"domain_scores_codex":[0.9978674,0.0004230078,0.0003478594,0.0004711222,0.0005663645,0.0003242432],"domain_scores_gemma":[0.9985142,0.0004015767,0.0002792422,0.0006332951,0.00009862022,0.00007304413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002076834,0.0004712857,0.03027607,0.0000826053,0.00003880991,0.00005763365,0.003026165,0.0004392966,0.9537668,0.0004070496,0.01101503,0.0002115746],"study_design_scores_gemma":[0.001209626,0.0006215412,0.4289717,0.00004837236,0.0001334783,0.00001191034,0.001017652,0.001523122,0.565457,0.0002875973,0.0004035491,0.0003144902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973058,0.0001742965,0.00001007732,0.0001773391,0.0009786087,0.0005198512,0.00005036273,0.00007809718,0.0007056075],"genre_scores_gemma":[0.9919606,0.00001790789,0.00001016657,0.00006715469,0.0000879691,0.00003196331,0.000003151109,0.00003132777,0.007789721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3986956,"threshold_uncertainty_score":0.602794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05129349263993922,"score_gpt":0.2772917836187593,"score_spread":0.2259982909788201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}