{"id":"W4367184214","doi":"10.1080/2162402x.2023.2204745","title":"Early response evaluation of PD-1 blockade in NSCLC patients through FDG-PET-CT and T cell profiling of tumor-draining lymph nodes","year":2023,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Bristol-Myers Squibb","keywords":"Medicine; Blockade; CD8; Lymph; Positron emission tomography; Pathological; Oncology; Imaging biomarker; Pathology; Internal medicine; Cancer research; Immune system; Nuclear medicine; Receptor; Immunology; Radiology; Magnetic resonance imaging","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013941,0.0001259231,0.0003688862,0.0002700665,0.00003591083,0.000003859334,0.00008279738,0.00003844729,0.0000400195],"category_scores_gemma":[0.0003240488,0.0001175283,0.00006072106,0.0005004532,0.0002188521,0.00007209108,0.00005507,0.0001192109,0.000006030598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001442891,"about_ca_system_score_gemma":0.0003311799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005152295,"about_ca_topic_score_gemma":0.000008092737,"domain_scores_codex":[0.9984347,0.0003444198,0.0004746208,0.0002294132,0.0002862194,0.0002306328],"domain_scores_gemma":[0.9990632,0.0002573727,0.0002386927,0.0002504312,0.0001736419,0.00001667967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01417427,0.0002668838,0.1990281,0.000142264,0.0001347174,0.00005072855,0.003601551,0.0000224984,0.7668681,0.00001694467,0.00001924649,0.01567469],"study_design_scores_gemma":[0.01149546,0.00076488,0.8625375,0.000318842,0.00008260691,0.00004124554,0.001571998,0.0003522766,0.1224937,0.0001081544,0.0001195769,0.0001137788],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996747,0.001503514,0.000002731391,0.0001929103,0.0001686226,0.0004185891,0.00001260918,0.00002760257,0.0009264024],"genre_scores_gemma":[0.9992529,0.0001759109,0.0003241278,0.00005602287,0.00001243918,0.00003611069,0.00002687282,0.00001970253,0.00009589782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6635094,"threshold_uncertainty_score":0.4792666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03555770407278394,"score_gpt":0.3185617188335017,"score_spread":0.2830040147607178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}