{"id":"W4367184303","doi":"10.1093/neuonc/noad082","title":"Mitogen-induced defective mitosis transforms neural progenitor cells","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; University of Calgary","funders":"Alberta Children's Hospital Foundation; Alberta Cancer Foundation; Canadian Institutes of Health Research; Alberta Innovates; Cancer Research Society","keywords":"Mitosis; Biology; Progenitor cell; Cell biology; Neural stem cell; Population; Cell division; Cancer research; Genetics; Stem cell; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001574647,0.0002980798,0.0003185367,0.0001241809,0.0001501484,0.00002449865,0.0003436249,0.0004840747,0.00002286995],"category_scores_gemma":[0.00007172123,0.0002828786,0.0002839304,0.0003180172,0.00009067511,0.000007214355,0.0001472353,0.0002817051,0.0002053658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005463565,"about_ca_system_score_gemma":0.0002111432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002325629,"about_ca_topic_score_gemma":0.00011134,"domain_scores_codex":[0.9980319,0.0001858541,0.000328458,0.0006753145,0.0001489767,0.0006295195],"domain_scores_gemma":[0.9991213,0.00007131357,0.0001038578,0.0004167572,0.0001023705,0.0001843678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001702845,0.0001004568,0.0004683068,0.00001830149,0.00007430097,0.00004593086,0.0001836116,0.00003313053,0.9757242,0.00001403643,0.006974592,0.01619286],"study_design_scores_gemma":[0.0009486143,0.001266103,0.0002602907,0.000002795715,0.00005115955,0.0000723425,0.0001478282,0.0002222633,0.8509548,0.00002118013,0.1457884,0.0002641602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950261,0.0001014961,0.000140173,0.0005077673,0.002323784,0.0006411211,0.00005642684,0.0001095828,0.001093598],"genre_scores_gemma":[0.9968017,0.0003838355,0.0001355163,0.001224921,0.0007629787,0.000196715,0.0001616718,0.00007738436,0.0002552825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1388138,"threshold_uncertainty_score":0.9999623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01619326943506174,"score_gpt":0.2737602912117679,"score_spread":0.2575670217767062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}