{"id":"W4367184303","doi":"10.1093/neuonc/noad082","title":"Mitogen-induced defective mitosis transforms neural progenitor cells","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; University of Calgary","funders":"Alberta Children's Hospital Foundation; Alberta Cancer Foundation; Canadian Institutes of Health Research; Alberta Innovates; Cancer Research Society","keywords":"Mitosis; Biology; Progenitor cell; Cell biology; Neural stem cell; Population; Cell division; Cancer research; Genetics; Stem cell; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001055363,0.0003080334,0.0001497861,0.0002522606,0.0001138866,0.0001889855,0.0001993695,0.0001687721,0.0009301326],"category_scores_gemma":[0.0001033173,0.0001026746,0.0001664805,0.0001535472,0.0001373203,0.00008697217,0.0001982112,0.0003841033,0.000351613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002777922,"about_ca_system_score_gemma":0.0002129064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006394641,"about_ca_topic_score_gemma":0.0008054813,"domain_scores_codex":[0.9999164,0.000009757629,0.00001162192,0.00001317156,0.00003571624,0.00001325489],"domain_scores_gemma":[0.9998765,0.00003435161,0.00003578818,0.00001993676,0.00001089246,0.00002253298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007239331,0.00003487533,0.0002197969,0.00002779305,0.000003351668,0.00007529077,0.00001891935,0.00008941615,0.9986021,0.0001382457,0.00001894118,0.0006989382],"study_design_scores_gemma":[0.00002034525,0.0003537394,0.002996851,0.000006580188,0.00001203206,0.0004283705,0.00001747853,0.001279619,0.9920447,0.00007268627,0.002764699,0.000002871164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951552,0.0005054503,0.002322023,0.00003098846,0.00001875035,0.0000408419,0.0004405149,0.00007169856,0.001414473],"genre_scores_gemma":[0.9938191,0.000454579,0.00262562,0.0000236638,0.000007151859,0.00006100626,0.00120207,0.00001957853,0.001787259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009301326,"threshold_uncertainty_score":0.003111601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01619326943506174,"score_gpt":0.2737602912117679,"score_spread":0.2575670217767062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}