{"id":"W4367187337","doi":"10.1016/j.euf.2023.04.001","title":"Predicting Mirabegron Treatment Response in Patients with Overactive Bladder: A Post Hoc Analysis of Data from Clinical Trials","year":2023,"lang":"en","type":"article","venue":"European Urology Focus","topic":"Urinary Bladder and Prostate Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Astellas Pharma Canada","keywords":"Medicine; Overactive bladder; Mirabegron; Urination; Post-hoc analysis; Confidence interval; Placebo; Tolerability; Urology; Urinary incontinence; Internal medicine; Randomized controlled trial; Urinary system; Adverse effect","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.09249227,0.001663114,0.004511264,0.001410351,0.0004419591,0.001755374,0.001222315,0.0008522597,0.00288443],"category_scores_gemma":[0.08114406,0.0004887755,0.01067383,0.001171447,0.0007863753,0.001524261,0.0007368501,0.002037111,0.0003286281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000806346,"about_ca_system_score_gemma":0.002019638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005074794,"about_ca_topic_score_gemma":0.0008983937,"domain_scores_codex":[0.9300432,0.06043588,0.00341284,0.002970428,0.002461132,0.0006766539],"domain_scores_gemma":[0.7918,0.1842972,0.01211826,0.006964211,0.003786932,0.001033491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2758869,0.002941034,0.3566954,0.009290628,0.2130749,0.0004783148,0.0004700817,0.02792,0.005486184,0.0007998638,0.007283918,0.09967265],"study_design_scores_gemma":[0.05339216,0.1571236,0.413851,0.001697766,0.1926213,0.001271049,0.0005770823,0.1453365,0.008865227,0.004114171,0.0207402,0.0004099485],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9224131,0.02230089,0.0338885,0.001906332,0.0008448238,0.007152416,0.008217226,0.0004247903,0.002851934],"genre_scores_gemma":[0.9812161,0.001035422,0.01070927,0.0004714276,0.0002105363,0.002752182,0.002964266,0.00007457603,0.000566136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09249227,"threshold_uncertainty_score":0.4891518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1773813160372381,"score_gpt":0.4400342323554468,"score_spread":0.2626529163182086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}