{"id":"W4367300152","doi":"10.15252/rc.2023574142","title":"Author Reply to Peer Reviews of MTCH2 cooperates with MFN2 and lysophosphatidic acid synthesis to sustain mitochondrial fusion","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Lysophosphatidic acid; MFN2; mitochondrial fusion; Chemistry; Fusion; Computational biology; Mitochondrial DNA; Biology; Biochemistry; Philosophy; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004726996,0.0008261451,0.001285523,0.001530094,0.002454672,0.003324714,0.002183942,0.01383116,0.03304851],"category_scores_gemma":[0.06196086,0.000570689,0.001086276,0.0007167882,0.001545037,0.002443751,0.00199252,0.01053652,0.02120425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002570685,"about_ca_system_score_gemma":0.004012501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00398409,"about_ca_topic_score_gemma":0.00556402,"domain_scores_codex":[0.9948115,0.0009528759,0.0005889795,0.0005417609,0.002450078,0.0006548521],"domain_scores_gemma":[0.9622074,0.007379089,0.001316894,0.001296832,0.02460778,0.003191968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005495582,0.000007107366,0.0001966083,0.00009155404,0.00001483675,0.0006140217,0.0000464622,0.00001907596,0.0001904737,0.0004506134,0.9942573,0.004056871],"study_design_scores_gemma":[0.00004101364,0.00002382351,0.0007756536,0.0001535553,0.00003104032,0.001189854,0.0002024965,0.0001688693,0.000673174,0.001082615,0.9956196,0.00003835611],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0008844566,0.003170276,0.0005226257,0.4990749,0.4912322,0.00004331895,0.0003361529,0.000183259,0.004552907],"genre_scores_gemma":[0.02200577,0.009391628,0.001699512,0.3748349,0.4454758,0.0001720912,0.001163879,0.0005853125,0.144671],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03304851,"threshold_uncertainty_score":0.1105583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02682126140773556,"score_gpt":0.3040466426142542,"score_spread":0.2772253812065186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}