{"id":"W4367301480","doi":"10.1016/j.ijrobp.2023.04.018","title":"Framework for Quality Assurance of Ultrahigh Dose Rate Clinical Trials Investigating FLASH Effects and Current Technology Gaps","year":2023,"lang":"en","type":"review","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Advanced Radiotherapy Techniques","field":"Physics and Astronomy","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria; McGill University Health Centre","funders":"National Institute of Biomedical Imaging and Bioengineering; National Cancer Institute; National Heart, Lung, and Blood Institute; University of Texas MD Anderson Cancer Center; Brain Tumour Charity; Canada Research Chairs; National Institutes of Health; Cancer Research UK; American Association of Physicists in Medicine; Damon Runyon Cancer Research Foundation; Varian Medical Systems; Patient-Centered Outcomes Research Institute; Medical Research Council; Cancer Prevention and Research Institute of Texas; University of Pennsylvania; Massachusetts General Hospital","keywords":"Credentialing; Quality assurance; Medical physics; Clinical trial; Medicine; Flash (photography); Modalities; Medical education; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.1667224,0.002384694,0.009073103,0.004819218,0.001383833,0.01016278,0.009418313,0.007909896,0.004708444],"category_scores_gemma":[0.1199688,0.00136753,0.005038061,0.002898617,0.004616971,0.006066771,0.005450696,0.009596428,0.002264576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01104339,"about_ca_system_score_gemma":0.06157453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006415175,"about_ca_topic_score_gemma":0.00590594,"domain_scores_codex":[0.9503491,0.02536526,0.009371855,0.002583251,0.01089494,0.001435632],"domain_scores_gemma":[0.8181339,0.1163086,0.02330693,0.006495536,0.03077928,0.004975709],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007873952,0.0002843376,0.001463263,0.06548458,0.001759892,0.0002439414,0.0005138417,0.003834852,0.001264972,0.08648516,0.05544633,0.7824314],"study_design_scores_gemma":[0.001046547,0.001214739,0.00458298,0.1732544,0.00357214,0.0007041343,0.0004641529,0.002721565,0.001369404,0.09916654,0.7117066,0.0001967423],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.0005202162,0.9260632,0.02048692,0.04269815,0.002688246,0.001974645,0.0006229332,0.0003758924,0.004569868],"genre_scores_gemma":[0.02653307,0.7591573,0.1563505,0.04170388,0.004254832,0.007402775,0.002116308,0.000180421,0.00230093],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.8332776,"threshold_uncertainty_score":0.8817231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1507339374130497,"score_gpt":0.5363639655981857,"score_spread":0.385630028185136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}