{"id":"W4367304448","doi":"10.1212/wnl.0000000000203363","title":"Efficacy and Safety of DaxibotulinumtoxinA for Injection Over Successive Treatments in Adults With Cervical Dystonia in the Phase 3 ASPEN-1 and ASPEN-OLS Trials (P11-11.006)","year":2023,"lang":"en","type":"article","venue":"Neurology","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Spasmodic Torticollis; Cervical dystonia; Placebo; Medicine; Botulinum toxin; Rating scale; Clinical trial; Physical therapy; Internal medicine; Anesthesia; Surgery; Psychology; Torticollis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003132344,0.0009085767,0.001477283,0.0003133773,0.0003869059,0.0008013952,0.0005054058,0.001069373,0.002859688],"category_scores_gemma":[0.001613275,0.0003626307,0.002604913,0.0003156439,0.0005692467,0.0006805663,0.0003738444,0.001739469,0.0002905232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001229829,"about_ca_system_score_gemma":0.001406851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002734565,"about_ca_topic_score_gemma":0.00697116,"domain_scores_codex":[0.9991369,0.0004730504,0.00007932971,0.000105015,0.000105787,0.0001000399],"domain_scores_gemma":[0.9990124,0.0002567561,0.0003644121,0.00004573942,0.00008758887,0.000233121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9140427,0.00817262,0.004297816,0.001134734,0.002685149,0.00007312674,0.000140517,0.0004615313,0.008526291,0.00009342017,0.001356273,0.05901577],"study_design_scores_gemma":[0.5660477,0.3946782,0.03256486,0.0001547933,0.002244596,0.0001562401,0.00007398341,0.0005893409,0.002084496,0.0001165821,0.001255459,0.00003374015],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899077,0.006296386,0.0002150142,0.0003452508,0.0000941515,0.001228553,0.0007122191,0.000026302,0.001174439],"genre_scores_gemma":[0.9921335,0.003631318,0.0007042754,0.000505131,0.0001891279,0.0009504404,0.001091801,0.000008788837,0.0007855155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003132344,"threshold_uncertainty_score":0.01656562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02936698705038488,"score_gpt":0.3354632218617304,"score_spread":0.3060962348113455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}