{"id":"W4367312487","doi":"10.1093/nar/gkad304","title":"Heat shock transcription factors demonstrate a distinct mode of interaction with mitotic chromosomes","year":2023,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canada Research Chairs; British Columbia Knowledge Development Fund; Michael Smith Health Research BC; Canada Foundation for Innovation","keywords":"Biology; Mitosis; Interphase; Cell biology; Heat shock factor; Transcription factor; Genetics; Cell division; Premature chromosome condensation; Cell; Cell cycle; Heat shock protein; Gene; Hsp70","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006190823,0.000237359,0.0001914662,0.0003838247,0.0001721477,0.0003872457,0.0001583393,0.0002343478,0.00116178],"category_scores_gemma":[0.0001074533,0.000177625,0.0001830982,0.0002033533,0.0001948479,0.0001947414,0.0002333901,0.0002625385,0.0003257419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002170077,"about_ca_system_score_gemma":0.00007849191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006265538,"about_ca_topic_score_gemma":0.001079812,"domain_scores_codex":[0.9999242,0.000004489018,0.000004121295,0.00002404899,0.00002689001,0.0000162053],"domain_scores_gemma":[0.9999021,0.00001450943,0.00002826894,0.00001405268,0.0000174332,0.00002364557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003331279,0.000002896196,0.0006621701,0.00002179489,0.000003884468,0.00002070557,0.00001692985,0.0000178671,0.9977891,0.0001059499,0.00001759401,0.001307784],"study_design_scores_gemma":[0.000007880077,0.0001558137,0.09398513,0.00001004948,0.00001373304,0.0005270627,0.00007525625,0.0005302412,0.8998067,0.0001689504,0.0047063,0.00001295196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791319,0.005173806,0.01152975,0.00006562693,0.00001700118,0.00001923807,0.0004373904,0.0001329435,0.003492281],"genre_scores_gemma":[0.9915285,0.001095669,0.002805181,0.00004440021,0.00001247284,0.00002707045,0.0005507485,0.00002088067,0.003915016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00116178,"threshold_uncertainty_score":0.00388658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02951049697310622,"score_gpt":0.3128596456351617,"score_spread":0.2833491486620555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}