{"id":"W4367313374","doi":"10.1111/epi.17631","title":"Perampanel for the treatment of people with idiopathic generalized epilepsy in clinical practice","year":2023,"lang":"en","type":"article","venue":"Epilepsia","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital","funders":"Eisai","keywords":"Perampanel; Idiopathic generalized epilepsy; Tolerability; Discontinuation; Epilepsy; Medicine; Pediatrics; Population; Adverse effect; Generalized epilepsy; Juvenile myoclonic epilepsy; Anesthesia; Psychiatry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008228743,0.0003140263,0.001379545,0.0006963577,0.0001745566,0.0007295464,0.0003902293,0.0004366985,0.001982882],"category_scores_gemma":[0.01072703,0.0002001745,0.001579129,0.00093527,0.0002901896,0.000623505,0.0006510898,0.000443925,0.0002135572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005445775,"about_ca_system_score_gemma":0.0009056713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006445979,"about_ca_topic_score_gemma":0.002025605,"domain_scores_codex":[0.992624,0.004689431,0.0009939249,0.0005995469,0.0009053614,0.0001876407],"domain_scores_gemma":[0.9944887,0.001580798,0.003243492,0.0001790793,0.0003600295,0.0001479104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0570458,0.001057015,0.2272825,0.02329778,0.05128301,0.0005686248,0.0006046073,0.0009739608,0.004395606,0.0005371671,0.004339348,0.6286146],"study_design_scores_gemma":[0.04316613,0.07734749,0.7475313,0.007846501,0.07445196,0.00623246,0.001211536,0.002439781,0.003660289,0.001434146,0.03454266,0.0001357788],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7104996,0.2773246,0.002389905,0.001903793,0.0002048445,0.001026604,0.001774444,0.00009488955,0.004781201],"genre_scores_gemma":[0.9772542,0.01907728,0.001613734,0.0006747401,0.0002151393,0.0003544059,0.0005395509,0.000006739156,0.0002643192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008228743,"threshold_uncertainty_score":0.0435183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06891987683109217,"score_gpt":0.4018146066699312,"score_spread":0.332894729838839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}