{"id":"W4367333626","doi":"10.1007/978-981-19-8520-1_3","title":"Alternative Splicing and Cancer","year":2023,"lang":"en","type":"book-chapter","venue":"","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Alternative splicing; Biology; Epigenetics; RNA splicing; Chromatin; Gene; Chromatin remodeling; Transcriptome; Cancer cell; Cell biology; Gene expression; Genetics; Computational biology; Cancer; RNA; Gene isoform","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002656762,0.0004333325,0.0003839533,0.0007519152,0.0004930967,0.00149805,0.0005640462,0.0008696973,0.02872621],"category_scores_gemma":[0.0002618373,0.000217493,0.000237703,0.001024394,0.0009634271,0.001173995,0.000912652,0.001553369,0.01142223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007920932,"about_ca_system_score_gemma":0.0005656756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008746456,"about_ca_topic_score_gemma":0.002278317,"domain_scores_codex":[0.9998568,0.00002213924,0.00000412646,0.00002525812,0.000075826,0.00001580973],"domain_scores_gemma":[0.9999453,0.00002486346,0.000003391903,0.000007261228,0.00001069281,0.000008518107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000536349,0.00004833358,0.00008313064,0.0003803623,0.00001121107,0.0002443412,0.0003103459,0.0003922352,0.007135914,0.2666476,0.2552751,0.4694178],"study_design_scores_gemma":[0.000002229341,0.00000881061,0.00006882948,0.00005790382,0.000002410721,0.0002621378,0.00003659141,0.00006943034,0.0008107238,0.02477381,0.9739042,0.000002868073],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.002362326,0.363399,0.008445159,0.009006747,0.006003164,0.00004809676,0.0002387665,0.0002362811,0.6102605],"genre_scores_gemma":[0.01378568,0.1359858,0.003972913,0.002918481,0.001438643,0.00006060055,0.0001862377,0.00009242903,0.8415592],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.02872621,"threshold_uncertainty_score":0.09609878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0277630741331351,"score_gpt":0.3054694832768051,"score_spread":0.27770640914367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}