{"id":"W4367395482","doi":"10.1093/humrep/dead085","title":"Human organoid systems in modeling reproductive tissue development, function, and disease","year":2023,"lang":"en","type":"review","venue":"Human Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Organoid; Biology; Blastocyst; Trophoblast; Embryonic stem cell; Stem cell; Bioinformatics; Fetus; Cell biology; Pregnancy; Placenta; Embryo; Embryogenesis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002221677,0.000753477,0.0008191348,0.001445657,0.0004878546,0.001981738,0.001044504,0.001590488,0.007046876],"category_scores_gemma":[0.001658991,0.0004565006,0.0009930062,0.001138518,0.0009452885,0.001393561,0.00145628,0.001759534,0.003520994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007612591,"about_ca_system_score_gemma":0.001488572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001788257,"about_ca_topic_score_gemma":0.00307284,"domain_scores_codex":[0.9992131,0.0002520076,0.00009178199,0.0001076747,0.0002820707,0.00005328566],"domain_scores_gemma":[0.9991943,0.0003920171,0.00010128,0.00007837396,0.0001798083,0.00005421536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003177235,0.0001481453,0.001931042,0.02181089,0.0002645803,0.002056709,0.001336295,0.01200129,0.1931226,0.0987678,0.06017852,0.6080644],"study_design_scores_gemma":[0.00001254313,0.0002276143,0.0007542971,0.001383809,0.00013425,0.001658421,0.0001743994,0.001441301,0.02403671,0.004809157,0.9653176,0.00004978752],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0102606,0.7475755,0.1818146,0.003062001,0.002814088,0.0007878005,0.003258828,0.001005457,0.04942105],"genre_scores_gemma":[0.08068652,0.7526459,0.132809,0.003197906,0.0007744742,0.001679884,0.004830174,0.0003575625,0.02301867],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007046876,"threshold_uncertainty_score":0.02357417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1416601881186915,"score_gpt":0.376135356058704,"score_spread":0.2344751679400125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}