{"id":"W4367397615","doi":"10.1053/j.gastro.2023.04.021","title":"Pharmacomicrobiomics in IBD: Should We Select Treatments Based on Gut Microbes?","year":2023,"lang":"en","type":"letter","venue":"Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Pharmacogenomics; Inflammatory bowel disease; Ulcerative colitis; Medicine; Inflammatory Bowel Diseases; Disease; Drug response; Gut flora; Bioinformatics; Intensive care medicine; Immunology; Drug; Internal medicine; Pharmacology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003856178,0.0006843625,0.002397991,0.0008034835,0.002494481,0.002665054,0.00128185,0.03262398,0.004604667],"category_scores_gemma":[0.0203932,0.0004554169,0.001290736,0.0006036976,0.003937937,0.004301076,0.001512376,0.03503246,0.002800856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003115861,"about_ca_system_score_gemma":0.003292331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001984527,"about_ca_topic_score_gemma":0.005036245,"domain_scores_codex":[0.9973428,0.001094572,0.0003942543,0.0002360684,0.0006318898,0.0003003966],"domain_scores_gemma":[0.9893236,0.006600104,0.0005704954,0.0002758753,0.001197904,0.002032099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003864051,0.0002381377,0.003117391,0.0001903349,0.00009800067,0.005258383,0.0001169794,0.0001811295,0.0004460757,0.009607851,0.923683,0.05667641],"study_design_scores_gemma":[0.001661137,0.0005770807,0.005138804,0.001621333,0.0002252857,0.01246859,0.0007759947,0.00135437,0.0005762833,0.08075433,0.8946253,0.0002215579],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004961478,0.006143366,0.0001377965,0.9795828,0.01189908,0.000007019557,0.00001430083,0.00001528132,0.001704135],"genre_scores_gemma":[0.008438327,0.005421297,0.00048641,0.8754705,0.1081275,0.00003543159,0.0000231356,0.00001625101,0.001981164],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03262398,"threshold_uncertainty_score":0.02260727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02856880480256394,"score_gpt":0.2950514458002048,"score_spread":0.2664826409976409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}