{"id":"W4367599261","doi":"10.1101/gr.277628.122","title":"CRISPR-Cas9-based repeat depletion for high-throughput genotyping of complex plant genomes","year":2023,"lang":"en","type":"article","venue":"Genome Research","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Saskatchewan Research Council (Canada); University of Saskatchewan","funders":"European Commission","keywords":"Biology; Genotyping; Genetics; Genome; CRISPR; Genomics; DNA sequencing; Computational biology; Cas9; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009574295,0.0001007291,0.0001856948,0.00006787188,0.0004931485,0.00004629938,0.0003032301,0.00008257685,0.0005677228],"category_scores_gemma":[0.0001109047,0.0000465686,0.00009241157,0.0009226626,0.00009465958,0.00003440919,0.0001329988,0.0001071418,0.000137233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005444922,"about_ca_system_score_gemma":0.00004011773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000445377,"about_ca_topic_score_gemma":0.0004001901,"domain_scores_codex":[0.9982996,0.0001386411,0.0002688182,0.0003489526,0.0004232334,0.000520756],"domain_scores_gemma":[0.9987866,0.000688576,0.00004325983,0.0001152793,0.0002706954,0.00009553193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006757397,0.00007382515,0.001739079,0.00006101428,0.00002347102,0.000003386147,0.0001537423,0.0002686694,0.9827737,0.001847884,0.0009104668,0.01207724],"study_design_scores_gemma":[0.0006989269,0.001173887,0.818276,0.00003956569,0.00002086167,0.000005785402,0.000678135,0.004275073,0.02334942,0.01127384,0.1398361,0.0003724276],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925993,0.0002423475,0.0001673489,0.005013457,0.00007736937,0.0007151471,0.0008163439,0.00008808076,0.0002806081],"genre_scores_gemma":[0.9968063,0.000142912,0.0008300759,0.0000491255,0.0003396694,0.000112927,0.00140884,0.000002467156,0.0003076548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9594242,"threshold_uncertainty_score":0.6216167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.193694194509419,"score_gpt":0.3517450806205367,"score_spread":0.1580508861111177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}