{"id":"W4367601047","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1295","title":"SUNRISE: A Phase 3, Parallel-group Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing OCS Use in OCS-dependent Patients With Severe Asthma","year":2023,"lang":"en","type":"article","venue":"","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Sunrise; Medicine; Phase (matter); Meteorology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002840626,0.001866941,0.003760963,0.0005634591,0.0008813814,0.001456069,0.00127339,0.001895807,0.004839851],"category_scores_gemma":[0.001778418,0.0007724948,0.00356807,0.0004673412,0.001694029,0.001558673,0.0004834865,0.005046786,0.0009028311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001017176,"about_ca_system_score_gemma":0.001996065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001502946,"about_ca_topic_score_gemma":0.004729419,"domain_scores_codex":[0.9991301,0.0003553844,0.00004928489,0.0001679898,0.000107527,0.000189754],"domain_scores_gemma":[0.9987956,0.0002577086,0.000198613,0.0001504165,0.00009735782,0.0005002834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9157757,0.03978199,0.001685675,0.0006826735,0.002248142,0.00007374509,0.0001764194,0.0006305237,0.008750559,0.0001495736,0.001361942,0.02868299],"study_design_scores_gemma":[0.8882095,0.1063841,0.003544209,0.00001610324,0.0004374482,0.00005534021,0.00003273878,0.0003035947,0.0004933485,0.0000819589,0.0004211798,0.0000206145],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900985,0.002064714,0.0008118778,0.0004660638,0.0003396408,0.003708985,0.001097767,0.0001831111,0.001229213],"genre_scores_gemma":[0.984531,0.001820428,0.003342833,0.001677566,0.0004204137,0.004281033,0.001803967,0.00007000798,0.002052729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004839851,"threshold_uncertainty_score":0.01619089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02366375499429403,"score_gpt":0.3151786970038388,"score_spread":0.2915149420095448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}