{"id":"W4367604579","doi":"10.1016/j.leukres.2023.107270","title":"Topic: AS08-Treatment/AS08f-Clinical trials – Phase II-III: RANDOMIZED PHASE 2 STUDY TO ASSESS SAFETY AND EFFICACY OF LOW-DOSE (LD) ORAL DECITABINE/CEDAZURIDINE (ASTX727) IN LOWER-RISK MYELODYSPLASTIC SYNDROMES (LR-MDS) PATIENTS: INTERIM SAFETY ANALYSIS","year":2023,"lang":"en","type":"article","venue":"Leukemia Research","topic":"Cardiac Imaging and Diagnostics","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta Hospital; Ottawa Regional Cancer Foundation","funders":"","keywords":"Medicine; Internal medicine; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003516848,0.001679927,0.002400719,0.0004213118,0.0004802436,0.001381158,0.001008141,0.002254231,0.01205616],"category_scores_gemma":[0.001959765,0.000599293,0.002253898,0.0003931083,0.0009093172,0.001021194,0.0003730407,0.003805947,0.002898288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000947773,"about_ca_system_score_gemma":0.001978453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006470853,"about_ca_topic_score_gemma":0.002402511,"domain_scores_codex":[0.9990607,0.0006136047,0.00004088757,0.0001025865,0.0000663176,0.0001159075],"domain_scores_gemma":[0.9985532,0.0002960475,0.0003863508,0.000138998,0.0001479601,0.0004773282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8639409,0.01667847,0.00272677,0.001633884,0.002200102,0.0001239265,0.000109249,0.001677485,0.01552668,0.0009069737,0.02540049,0.06907515],"study_design_scores_gemma":[0.9068468,0.08056054,0.002596948,0.00007315195,0.0005537316,0.0001092421,0.00002342934,0.0005845301,0.001205414,0.0004862977,0.006937774,0.00002215505],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9280498,0.01007057,0.003426161,0.007609796,0.001327711,0.0174532,0.0178507,0.0008186378,0.01339335],"genre_scores_gemma":[0.8827851,0.008085422,0.01825354,0.01129979,0.001743254,0.02770097,0.02321495,0.0003078716,0.02660904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01205616,"threshold_uncertainty_score":0.0403319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1566909210018332,"score_gpt":0.5137303052899491,"score_spread":0.357039384288116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}