{"id":"W4367604579","doi":"10.1016/j.leukres.2023.107270","title":"Topic: AS08-Treatment/AS08f-Clinical trials – Phase II-III: RANDOMIZED PHASE 2 STUDY TO ASSESS SAFETY AND EFFICACY OF LOW-DOSE (LD) ORAL DECITABINE/CEDAZURIDINE (ASTX727) IN LOWER-RISK MYELODYSPLASTIC SYNDROMES (LR-MDS) PATIENTS: INTERIM SAFETY ANALYSIS","year":2023,"lang":"en","type":"article","venue":"Leukemia Research","topic":"Cardiac Imaging and Diagnostics","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta Hospital; Ottawa Regional Cancer Foundation","funders":"","keywords":"Medicine; Internal medicine; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.02233888,0.0005339051,0.004910931,0.002369941,0.0002829025,0.0001090919,0.0003341656,0.0002113087,0.0003126136],"category_scores_gemma":[0.080755,0.0004054467,0.001071379,0.004426542,0.000498766,0.0001518407,0.0006444196,0.0009663575,0.00006170299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001064318,"about_ca_system_score_gemma":0.001019772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001722466,"about_ca_topic_score_gemma":0.0002425952,"domain_scores_codex":[0.9873269,0.005913469,0.002999194,0.001193966,0.001546467,0.001020004],"domain_scores_gemma":[0.9632925,0.03338727,0.0004398936,0.001193732,0.0008708762,0.0008156961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6830985,0.0296081,0.1474604,0.0002413851,0.008815153,0.001768076,0.003554154,0.001131158,0.0003934058,0.00003305654,0.00295567,0.1209409],"study_design_scores_gemma":[0.8168233,0.01435335,0.1525098,0.0004958395,0.004549813,0.00001022957,0.001415384,0.00818616,0.0002710019,0.00002539163,0.0009013138,0.0004583941],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919413,0.0002144654,0.00064387,0.0004474752,0.00055624,0.005359319,0.0004549783,0.0001059577,0.0002764222],"genre_scores_gemma":[0.9962965,0.001236991,0.0002283658,0.00004800519,0.0002506347,0.0002612697,0.0005647194,0.00006292438,0.001050641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1337248,"threshold_uncertainty_score":0.9998397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1566909210018332,"score_gpt":0.5137303052899491,"score_spread":0.357039384288116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}