{"id":"W4367606528","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4029","title":"MicroRNA-155 Delays Bronchial Epithelial Cells Repair by Differentially Modulating IL-13Rα1 and IL-13Rα2 Pathways in Severe Asthma","year":2023,"lang":"en","type":"article","venue":"","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"microRNA; Asthma; Signal transduction; Cell biology; Medicine; Immunology; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004852603,0.0005085564,0.0006642566,0.0002684642,0.0004079144,0.00005060447,0.0003240923,0.0006633225,0.0003581604],"category_scores_gemma":[0.00009850691,0.0004656515,0.0002224035,0.0003929135,0.0002473862,0.0001989976,0.0003910223,0.0006434797,0.001069029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007288065,"about_ca_system_score_gemma":0.0001318495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005478984,"about_ca_topic_score_gemma":0.0005752118,"domain_scores_codex":[0.9968135,0.000358493,0.0007349639,0.0008960736,0.00009813353,0.001098852],"domain_scores_gemma":[0.998952,0.0002425225,0.0001742239,0.0004687794,0.00007712399,0.00008539011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001912469,0.0001539818,0.001380725,0.00006049492,0.0001276274,0.00005189263,0.001579711,0.0000355686,0.9728803,0.00085683,0.01774099,0.00494064],"study_design_scores_gemma":[0.01134123,0.001289543,0.0244731,0.0002163543,0.0001209934,0.0004122825,0.002455393,0.001425653,0.8100634,0.001952084,0.1438486,0.002401387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882743,0.0002756927,0.0003440988,0.00008404991,0.001489343,0.0004459845,0.005786888,0.0006521834,0.002647416],"genre_scores_gemma":[0.9919115,0.0002708363,0.0003307512,0.0002379778,0.000166767,0.00003380738,0.0007911114,0.00007136339,0.00618592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1628169,"threshold_uncertainty_score":0.9997795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01099139207597404,"score_gpt":0.2040973797330941,"score_spread":0.1931059876571201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}