{"id":"W4367608157","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2181","title":"Rise of the Resistance: Cannabis Is Cytoprotective of Lymphangioleiomyomatosis (LAM) Cells but Fuels Lung Epithelium Dysregulation to Drive Stress-induced Premature Senescence","year":2023,"lang":"en","type":"article","venue":"","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; CReATe Fertility Centre","funders":"","keywords":"Lymphangioleiomyomatosis; Senescence; Lung; Epithelium; Cell biology; Medicine; Biology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001480247,0.0002985727,0.0003180423,0.0003624363,0.0005788713,0.0009300727,0.0002663082,0.000620522,0.006105612],"category_scores_gemma":[0.000303261,0.0002009923,0.0004205433,0.0001562785,0.0004910287,0.0004682444,0.0006378292,0.001556301,0.0009343027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006049033,"about_ca_system_score_gemma":0.0005711872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002018726,"about_ca_topic_score_gemma":0.004380916,"domain_scores_codex":[0.9996955,0.00003496379,0.00001194916,0.00005727227,0.00008884168,0.0001115511],"domain_scores_gemma":[0.9997849,0.00001725016,0.00003514223,0.00002117567,0.00004311896,0.00009840883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005578459,0.00004308153,0.001401159,0.0001101689,0.00001968661,0.0002223334,0.00006660227,0.00002503721,0.9919434,0.0006138372,0.0004735201,0.004523394],"study_design_scores_gemma":[0.0001098788,0.0009065028,0.06142735,0.0001259433,0.0001823583,0.001772056,0.0008783914,0.0007977134,0.8975373,0.001480122,0.03473209,0.00005035423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736762,0.01101862,0.002778068,0.003026869,0.0004363463,0.00007120672,0.001138403,0.0003724648,0.007481816],"genre_scores_gemma":[0.9895271,0.0020678,0.0007007331,0.0004593412,0.00006437157,0.00002651582,0.0003273835,0.00004013767,0.006786555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006105612,"threshold_uncertainty_score":0.02042526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01079883138348628,"score_gpt":0.2742771799036273,"score_spread":0.2634783485201411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}