{"id":"W4367856451","doi":"10.1016/j.brs.2023.04.022","title":"Serial electroconvulsive Seizure alters dendritic complexity and promotes cellular proliferation in the mouse dentate gyrus; a role for Egr3","year":2023,"lang":"en","type":"article","venue":"Brain stimulation","topic":"Electroconvulsive Therapy Studies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University","funders":"National Institute of Mental Health; National Institutes of Health","keywords":"Neurogenesis; Dentate gyrus; Hippocampal formation; Dendritic spine; Neuroscience; Bromodeoxyuridine; Hippocampus; Downregulation and upregulation; Neurotrophic factors; Cell biology; Biology; Chemistry; Immunohistochemistry; Medicine; Internal medicine; Immunology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000488985,0.0001713334,0.0002492213,0.0001572081,0.0002099592,0.00004808778,0.00006385178,0.00006731498,0.000006196729],"category_scores_gemma":[0.0003056424,0.0001375128,0.00005054637,0.0003329672,0.00007708548,0.00013165,0.00002024545,0.0001421339,0.000007480494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007928137,"about_ca_system_score_gemma":0.00004924064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002930663,"about_ca_topic_score_gemma":0.0001915493,"domain_scores_codex":[0.9987423,0.0001562522,0.0002611542,0.0002913311,0.0002161155,0.0003328392],"domain_scores_gemma":[0.9992045,0.000396432,0.00008128172,0.0001499971,0.0001264779,0.00004132182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001685116,0.0001487977,0.02304094,0.0002464335,0.0001232594,0.00002278563,0.01088684,0.0004130666,0.9581359,0.001768949,0.001207911,0.00232003],"study_design_scores_gemma":[0.02505699,0.005546328,0.3624901,0.0002284364,0.0004032392,0.0001466757,0.004789152,0.2455376,0.3060709,0.04714491,0.001568583,0.00101709],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887903,0.0001455403,0.001385114,0.006003515,0.00003447601,0.003496744,0.00001390919,0.0001036583,0.0000266997],"genre_scores_gemma":[0.9972405,0.0000182841,0.0005352633,0.0009096412,0.0002303961,0.0004608592,0.0003782533,0.00002934796,0.000197453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.652065,"threshold_uncertainty_score":0.5607609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03276344084283093,"score_gpt":0.3114253611154072,"score_spread":0.2786619202725762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}