{"id":"W4368282868","doi":"10.1039/d3sc00400g","title":"Arsenic binding to human metallothionein-3","year":2023,"lang":"en","type":"article","venue":"Chemical Science","topic":"Trace Elements in Health","field":"Nursing","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Metallothionein; Arsenic; Chemistry; Arsenic toxicity; Arsenic poisoning; Toxicity; Biochemistry; Environmental chemistry; Organic chemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000179704,0.0001724778,0.0001525877,0.0001096189,0.0002761558,0.000158628,0.0002490071,0.0001539858,0.002319721],"category_scores_gemma":[0.0003789013,0.00009789009,0.0001979636,0.0001774012,0.0001630973,0.0001134869,0.0001411056,0.0002785167,0.0002723888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002843073,"about_ca_system_score_gemma":0.0001499871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002820004,"about_ca_topic_score_gemma":0.003043865,"domain_scores_codex":[0.9998497,0.00003099097,0.000006202014,0.00003727982,0.00005120225,0.00002455282],"domain_scores_gemma":[0.999842,0.00006057018,0.00002992979,0.00001084527,0.00003438399,0.00002221416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005113496,0.00005832627,0.004964266,0.0001124373,0.00004160566,0.00009644093,0.00007345353,0.001109717,0.9892987,0.0002893552,0.0003206,0.003123699],"study_design_scores_gemma":[0.00002507577,0.0003746599,0.02871032,0.00000716331,0.00001761369,0.0005631348,0.0000879386,0.008095225,0.9587733,0.000398002,0.002920927,0.00002669673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952435,0.0007936027,0.002738637,0.00008137966,0.00001767494,0.000008231188,0.0002199305,0.00005071013,0.0008462642],"genre_scores_gemma":[0.9970189,0.0001966763,0.0009425411,0.00002785489,0.000006264795,0.000004406942,0.0003811738,0.00001312913,0.001408962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002820004,"threshold_uncertainty_score":0.007760227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0558877769144063,"score_gpt":0.3882677645781595,"score_spread":0.3323799876637532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}