{"id":"W4368347551","doi":"10.1126/science.adg2992","title":"Common genetic factors among autoimmune diseases","year":2023,"lang":"en","type":"review","venue":"Science","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institute of Neurological Disorders and Stroke; National Human Genome Research Institute; National Institutes of Health","keywords":"Disease; Genome-wide association study; Biology; Autoimmune disease; Genetic association; Genetics; Immune system; Evolutionary biology; Gene; Computational biology; Medicine; Genotype; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002857435,0.0005162922,0.001530107,0.0005391649,0.0007465313,0.00007149958,0.002019723,0.0005188108,0.0004242],"category_scores_gemma":[0.0001660133,0.0003701717,0.0004318196,0.001347362,0.003766453,0.0001349187,0.0007899494,0.0007033006,0.005514358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001306958,"about_ca_system_score_gemma":0.0006596409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001746228,"about_ca_topic_score_gemma":0.00002451906,"domain_scores_codex":[0.9971141,0.0002804419,0.0006673592,0.0008840509,0.00009875334,0.0009552968],"domain_scores_gemma":[0.9981427,0.0003486761,0.0004009639,0.0009928972,0.00005727446,0.00005751029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007264885,0.0002584435,0.001498988,0.003562249,0.0004347691,0.00007675796,0.000259277,0.000001583503,0.01964523,0.0002494996,0.001836903,0.972169],"study_design_scores_gemma":[0.0001539044,0.0000878183,0.004271279,0.001862632,0.0004100259,0.0000466622,0.0000550021,5.013341e-7,0.0003293412,0.00008672813,0.992181,0.0005150955],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006808802,0.9883533,0.000002466712,0.000007051703,0.003557399,0.0004996986,0.0001127926,0.000340864,0.0003176188],"genre_scores_gemma":[0.003679353,0.9852155,0.00000679019,0.0000123913,0.00003235561,0.0000656766,0.000230067,0.00005037158,0.01070748],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9903441,"threshold_uncertainty_score":0.999875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0396508988023121,"score_gpt":0.3001171169172797,"score_spread":0.2604662181149676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}