{"id":"W4368355226","doi":"10.1261/rna.079598.123","title":"On the origin of life: an RNA-focused synthesis and narrative","year":2023,"lang":"en","type":"article","venue":"RNA","topic":"Origins and Evolution of Life","field":"Physics and Astronomy","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto; Dalhousie University; University of California, Los Angeles; York University; Universities Space Research Association","keywords":"Biology; RNA world hypothesis; RNA; Abiogenesis; Transcription (linguistics); Evolutionary biology; DNA; Ancestor; Assertion; Genome; Genetics; Gene; Ribozyme; Archaeology; History","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001168834,0.00006187776,0.00009493774,0.00002974401,0.0001107848,0.00001615861,0.00007028301,0.00001366995,0.0005156877],"category_scores_gemma":[0.00001600232,0.0000402319,0.00003190136,0.0001205789,0.00004004005,0.00005040957,0.0000153794,0.00005483499,0.00005303261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004769678,"about_ca_system_score_gemma":0.00002964774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001139192,"about_ca_topic_score_gemma":0.000002250438,"domain_scores_codex":[0.9995942,0.00003697612,0.00008830949,0.00009559205,0.00008633186,0.00009860449],"domain_scores_gemma":[0.9995931,0.0001542392,0.00004659421,0.0001357681,0.00001888702,0.00005142763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","study_design_scores_codex":[0.00008454897,0.0002201223,0.02279547,0.00002218729,0.0002331342,0.000001468294,0.004995223,0.0002139616,0.003842347,0.8667725,0.06722386,0.03359514],"study_design_scores_gemma":[0.004221729,0.00169899,0.2525842,0.0006449291,0.0003048584,9.623591e-7,0.05528114,0.0330601,0.1589752,0.2430461,0.2476528,0.002529054],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909989,0.000006373824,0.00005069259,0.00110884,0.00006888698,0.00005805577,0.00004058747,0.00001971441,0.00764793],"genre_scores_gemma":[0.9991832,0.000002709009,0.00003436775,0.00004319991,0.0001598595,0.00001188046,0.0000030589,0.00000695278,0.000554741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6237264,"threshold_uncertainty_score":0.5646419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02652147219763089,"score_gpt":0.2650957906428306,"score_spread":0.2385743184451997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}