{"id":"W4368356128","doi":"10.1002/cyto.b.22123","title":"Summary of validation considerations with real‐life examples using both qualitative and semiquantitative flow cytometry assays","year":2023,"lang":"en","type":"article","venue":"Cytometry Part B Clinical Cytometry","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Repeatability; Reproducibility; Flow cytometry; Computer science; Paroxysmal nocturnal hemoglobinuria; Medicine; Chromatography; Immunology; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004936802,0.0005225061,0.00147216,0.001935863,0.0004974235,0.00007737105,0.0003234839,0.0004941307,0.00102307],"category_scores_gemma":[0.008479494,0.0004684078,0.0002934589,0.003895822,0.001420358,0.0004320614,0.0004036441,0.000608846,0.0002613689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001138884,"about_ca_system_score_gemma":0.0004409656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001223838,"about_ca_topic_score_gemma":0.00002827398,"domain_scores_codex":[0.9926485,0.003032917,0.002137051,0.001075355,0.0003516068,0.0007545236],"domain_scores_gemma":[0.9797899,0.01757029,0.001050584,0.000814763,0.0005405474,0.0002339964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001318868,0.001275922,0.8893563,0.0009612176,0.00390914,0.00009263078,0.003268476,0.0002448811,0.05367355,0.005803581,0.03918771,0.0009077615],"study_design_scores_gemma":[0.01953955,0.005495341,0.8461087,0.002671721,0.002411406,0.0002874479,0.06392901,0.001655086,0.03944917,0.004788317,0.009673487,0.003990743],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882638,0.001557246,0.005500965,0.0001982109,0.000814368,0.00086704,0.001730989,0.0003670814,0.0007003319],"genre_scores_gemma":[0.9944845,0.0005174605,0.003163087,0.0001760092,0.0001452447,0.00006763314,0.0009332296,0.00007672803,0.0004361341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06066053,"threshold_uncertainty_score":0.9998901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.227451889729768,"score_gpt":0.4468819064820767,"score_spread":0.2194300167523087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}