{"id":"W4368358973","doi":"10.1530/rep-22-0424","title":"DOHaD: A Menagerie of Adaptations and Perspectives: The interplay between early embryo metabolism and mitoepigenetic programming of development","year":2023,"lang":"en","type":"review","venue":"Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Epigenetics; Biology; Mitochondrial DNA; Mitochondrion; DNA methylation; mitochondrial fusion; Cell biology; Genetics; Regulation of gene expression; Retrograde signaling; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005843637,0.0001852363,0.0004827304,0.0001105117,0.0000821112,0.00001908737,0.00009222155,0.0001530184,9.406327e-7],"category_scores_gemma":[0.0002056994,0.0001368028,0.00009832838,0.000209062,0.0001444823,0.000003892811,0.000118674,0.0001023241,6.822524e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001160603,"about_ca_system_score_gemma":0.0001360363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002521424,"about_ca_topic_score_gemma":0.00001304852,"domain_scores_codex":[0.9985916,0.0001456168,0.0004947038,0.0005180216,0.0001306019,0.0001194351],"domain_scores_gemma":[0.9989915,0.00003889094,0.0004126042,0.0003828189,0.0001400639,0.00003409455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004490561,0.00001878493,0.00005935685,0.001567782,0.0003226498,1.406877e-7,0.001231224,0.000002695312,0.0019387,0.00003561964,0.000004074027,0.9948145],"study_design_scores_gemma":[0.0001859444,0.0002334021,0.007920489,0.001443567,0.001087235,0.000007030786,0.001043911,0.000001461346,0.01523973,0.0001313715,0.9723335,0.0003723674],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06217145,0.9365377,0.0005170516,0.00002164149,0.00009615757,0.000613835,0.00001235743,0.000007758405,0.0000219775],"genre_scores_gemma":[0.01956608,0.9778448,0.001896375,4.12138e-7,0.0002615257,0.00008558168,0.0000901634,0.00003338047,0.0002216188],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9944421,"threshold_uncertainty_score":0.5578656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05092211009693993,"score_gpt":0.3381958064664567,"score_spread":0.2872736963695168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}