{"id":"W4368372321","doi":"10.1038/s41568-023-00567-5","title":"The role of eIF4F-driven mRNA translation in regulating the tumour microenvironment","year":2023,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Translation (biology); Messenger RNA; Cell biology; Tumor microenvironment; Biology; Cancer research; Computational biology; Genetics; Gene; Tumor cells","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008974574,0.001375443,0.001919364,0.0013751,0.0003265155,0.001602613,0.001332739,0.002276843,0.003254554],"category_scores_gemma":[0.0007442211,0.0004686518,0.0005311799,0.002239152,0.001060878,0.001651713,0.001192747,0.003098402,0.003167981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001504105,"about_ca_system_score_gemma":0.00126883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009569848,"about_ca_topic_score_gemma":0.001829016,"domain_scores_codex":[0.9997559,0.00003315561,0.00002929987,0.00004603214,0.00009575913,0.0000398655],"domain_scores_gemma":[0.9995029,0.000223145,0.00006981754,0.00001653041,0.0001208176,0.0000667818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002357587,0.00005281888,0.0001462973,0.01331846,0.00009047856,0.000224031,0.0000332739,0.0009525395,0.006797308,0.01053338,0.07848345,0.8891323],"study_design_scores_gemma":[0.00003863218,0.00008787592,0.0006531359,0.001972301,0.00007867358,0.0007713879,0.00003562148,0.0002352552,0.001204751,0.004404669,0.9904913,0.00002636662],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005947945,0.9982666,0.0001277784,0.0004470087,0.0005253745,0.000001933378,0.00001959926,0.000007410824,0.0005447918],"genre_scores_gemma":[0.0004472623,0.9984829,0.00008844784,0.0002506898,0.0003054864,0.000003325509,0.0000270947,0.0000016008,0.0003931405],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003254554,"threshold_uncertainty_score":0.01091313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0307837588425917,"score_gpt":0.3411678447552786,"score_spread":0.3103840859126868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}