{"id":"W4368405349","doi":"10.3390/biom13050787","title":"Role of Angiotensin II in Cardiovascular Diseases: Introducing Bisartans as a Novel Therapy for Coronavirus 2019","year":2023,"lang":"en","type":"review","venue":"Biomolecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Victoria University","keywords":"Downregulation and upregulation; Angiotensin II; Angiotensin-converting enzyme 2; Medicine; Oxidative stress; Renin–angiotensin system; Coronavirus; Angiotensin receptor; Phenotype; Homeostasis; Receptor; Immunology; Coronavirus disease 2019 (COVID-19); Bioinformatics; Disease; Internal medicine; Biology; Gene; Blood pressure; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003676526,0.0002814947,0.0004729385,0.0004471626,0.0001592947,0.0006090144,0.000347738,0.0005646664,0.00207148],"category_scores_gemma":[0.0003605533,0.00009007504,0.0004012824,0.0002019035,0.0002254922,0.0006165395,0.0002732474,0.002248032,0.0006491001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002403844,"about_ca_system_score_gemma":0.0003089472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000315069,"about_ca_topic_score_gemma":0.001016327,"domain_scores_codex":[0.9998754,0.00003374993,0.0000182316,0.00002154143,0.00003246355,0.00001865014],"domain_scores_gemma":[0.9998801,0.00004213075,0.00002077332,0.000004191588,0.00002987085,0.00002298559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001057572,0.0006247048,0.0008857507,0.004416695,0.0003023169,0.001127703,0.0001306436,0.0004412283,0.03003401,0.01168848,0.03011725,0.9191736],"study_design_scores_gemma":[0.0005981997,0.002951967,0.003265902,0.001268297,0.000570246,0.004132326,0.0001143096,0.001481253,0.01407427,0.005977124,0.9654888,0.00007721147],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00815175,0.9753043,0.002671271,0.004732462,0.002053259,0.0000366352,0.00008651426,0.00009244303,0.006871408],"genre_scores_gemma":[0.07981757,0.8931552,0.005935804,0.007654565,0.004202546,0.00008477183,0.0003142682,0.00003276934,0.008802565],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00207148,"threshold_uncertainty_score":0.006929755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.033676929894979,"score_gpt":0.3161959387547155,"score_spread":0.2825190088597365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}