{"id":"W4372319622","doi":"10.1177/10870547231172767","title":"Real-World Efficacy and Safety of Extended-Release Methylphenidate (PRC-063) in the Treatment of ADHD in Pediatric and Adult Subjects: Results of a Phase IV Multicenter Comparison With Lisdexamfetamine Dimesylate","year":2023,"lang":"en","type":"article","venue":"Journal of Attention Disorders","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut universitaire en santé mentale de Montréal; Institut Universitaire en Santé Mentale de Québec; Ontario Centre of Excellence for Child and Youth Mental Health","funders":"","keywords":"Methylphenidate; Discontinuation; Psychology; Rating scale; Adverse effect; Stimulant; Population; Clinical endpoint; Evening; Psychiatry; Internal medicine; Pediatrics; Medicine; Clinical trial; Attention deficit hyperactivity disorder; Developmental psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007066415,0.0002216544,0.00082786,0.0009893507,0.00003136782,0.0000100393,0.00008916044,0.00006630187,0.00001184878],"category_scores_gemma":[0.0002680598,0.0001462968,0.0001548157,0.001205977,0.0001562055,0.0002067619,0.00002295047,0.0002303249,9.516392e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005118333,"about_ca_system_score_gemma":0.00006915159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004056513,"about_ca_topic_score_gemma":0.001238133,"domain_scores_codex":[0.9973341,0.0002810139,0.001428421,0.0002390547,0.0004964303,0.0002209369],"domain_scores_gemma":[0.9976441,0.0005139368,0.001246708,0.0002457234,0.0002624143,0.00008713127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02862542,0.01390998,0.9177739,0.0006725839,0.000419043,0.00008238572,0.008867097,0.0009049292,0.005497631,0.00002795941,0.0001144754,0.02310457],"study_design_scores_gemma":[0.05482234,0.003797398,0.92731,0.0003615529,0.0006280728,0.00001680395,0.01059654,0.002097024,0.000153092,0.00001574891,0.00007500018,0.000126343],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969228,0.00069069,0.00005991089,0.001409528,0.00004689961,0.0007390691,0.00003131347,0.000008155655,0.00009167014],"genre_scores_gemma":[0.9895591,0.01002871,0.0002085726,0.00001320672,0.0000283923,0.000008355197,0.00003999302,0.00002209337,0.00009160504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02619692,"threshold_uncertainty_score":0.596581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03176168405148042,"score_gpt":0.3513690348474585,"score_spread":0.319607350795978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}