{"id":"W4375851419","doi":"10.1016/j.cryobiol.2023.05.002","title":"Chilling injury in human kidney tubule cells after subzero storage is not mitigated by antifreeze protein addition","year":2023,"lang":"en","type":"article","venue":"Cryobiology","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Antifreeze protein; Antifreeze; Cryoprotectant; Cold storage; Kidney; Chemistry; Cell biology; Cryopreservation; Biochemistry; Biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002403223,0.0002587137,0.0002577869,0.0001276876,0.0001053311,0.00002667063,0.0002608666,0.0004434032,0.0002840051],"category_scores_gemma":[0.00005174987,0.0002760048,0.00009250338,0.0001796681,0.000191634,0.00000579132,0.0001662342,0.0002170918,0.0001458554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002463216,"about_ca_system_score_gemma":0.00006167445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007659683,"about_ca_topic_score_gemma":0.00003628532,"domain_scores_codex":[0.9982718,0.0001420321,0.0003374732,0.0006336452,0.00009117905,0.0005238318],"domain_scores_gemma":[0.9992473,0.000007569945,0.00009717573,0.0004463876,0.00006174519,0.0001398514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005499242,0.00005963319,0.001409654,0.00003048801,0.00002609832,0.00001136093,0.0002160503,0.00003114369,0.9625447,0.000007434786,0.03547751,0.000130946],"study_design_scores_gemma":[0.0005326015,0.0003070916,0.003512566,0.0000287384,0.00001221144,0.00000367421,0.00003017138,0.0001039878,0.9589579,0.0001416853,0.03602462,0.0003447202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976078,0.0001303682,0.0002902219,0.0004059986,0.0002550292,0.0003923139,0.0007624647,0.00005885343,0.00009697572],"genre_scores_gemma":[0.9937355,0.0001104819,0.0001452636,0.001785897,0.000219155,0.0001061723,0.002379396,0.00005108453,0.001467078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003872303,"threshold_uncertainty_score":0.9999692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006641745582621897,"score_gpt":0.226852664025798,"score_spread":0.2202109184431761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}