{"id":"W4375864585","doi":"10.1101/2023.05.04.539432","title":"Testing a candidate meiotic drive locus identified by pool sequencing","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton; University of British Columbia","funders":"National Institutes of Health","keywords":"Meiotic drive; Genetics; Mendelian inheritance; Biology; Locus (genetics); Genotyping; Allele; Meiosis; Candidate gene; Backcrossing; Evolutionary biology; Computational biology; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009296103,0.0005160951,0.0004812693,0.0004669849,0.0003479207,0.0004308576,0.0003946781,0.000658166,0.003330082],"category_scores_gemma":[0.0009683762,0.0002397792,0.0003445499,0.0002561182,0.0002652156,0.0003055245,0.0006054793,0.0005442564,0.001084188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002078359,"about_ca_system_score_gemma":0.0002386532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005065051,"about_ca_topic_score_gemma":0.001149114,"domain_scores_codex":[0.9994685,0.00008667753,0.00005172599,0.0001758906,0.0001596684,0.00005760438],"domain_scores_gemma":[0.999159,0.0003566901,0.0001267215,0.0001472423,0.00009523117,0.0001150329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007229659,0.00003775259,0.00461585,0.00003547904,0.0000224392,0.0001902835,0.0000420352,0.0002641654,0.9912328,0.0001832461,0.00008949116,0.003214117],"study_design_scores_gemma":[0.00002322687,0.0004886382,0.03864458,0.00001407673,0.00006962407,0.001135193,0.00009508507,0.00549684,0.9495931,0.0004361605,0.003978219,0.00002530431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9538403,0.0003643146,0.04106431,0.0001175346,0.00003602583,0.0001339952,0.001791531,0.0003850275,0.002267056],"genre_scores_gemma":[0.944104,0.0002265824,0.04751206,0.0002989745,0.00001212708,0.0002108342,0.002617712,0.0002704569,0.004747315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003330082,"threshold_uncertainty_score":0.01114023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01487585936180758,"score_gpt":0.2287947875953402,"score_spread":0.2139189282335327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}