{"id":"W4375955948","doi":"10.1186/s12964-023-01123-2","title":"TGF-β1 upregulates secreted protein acidic and rich in cysteine expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome","year":2023,"lang":"en","type":"article","venue":"Cell Communication and Signaling","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Zhengzhou University; First Affiliated Hospital of Zhengzhou University; University of British Columbia; National Natural Science Foundation of China","keywords":"Gene knockdown; Downregulation and upregulation; Transforming growth factor; Ovarian hyperstimulation syndrome; Granulosa cell; Follicular fluid; Andrology; Biology; Follicular phase; Cell biology; Chemistry; Endocrinology; Oocyte; Internal medicine; Cell culture; In vitro fertilisation; Medicine; Gene; Embryo; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005794613,0.0001178495,0.0002606986,0.0001782874,0.0002263249,0.00001858881,0.00009350014,0.0000924242,0.000005865887],"category_scores_gemma":[0.0000329481,0.0000931781,0.00003998402,0.0002894747,0.00008844298,0.00006530574,0.0001424117,0.0001241002,7.013686e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001853423,"about_ca_system_score_gemma":0.00001224758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001974149,"about_ca_topic_score_gemma":0.00003620873,"domain_scores_codex":[0.9990482,0.0001385128,0.0003589834,0.0001780778,0.0001365312,0.0001396467],"domain_scores_gemma":[0.99933,0.0001503721,0.0001250642,0.0002955335,0.00006513024,0.00003385418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001287492,0.00004977789,0.0004091407,0.0002513192,0.00001225231,0.000005603294,0.001270478,0.0002277302,0.9970593,0.0002287981,0.000002879642,0.0003539395],"study_design_scores_gemma":[0.006406074,0.0004522685,0.02262619,0.001402282,0.0001301983,0.00001839121,0.007276943,0.06779721,0.8874964,0.006110991,0.00001298867,0.0002700384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949806,0.002320552,0.001024821,0.0003164216,0.00001312546,0.001273739,0.000006138933,0.00003082197,0.00003378488],"genre_scores_gemma":[0.9979147,0.0002962049,0.001423423,0.00002595133,0.000008649055,0.0001713914,0.00005814012,0.00001686638,0.00008467524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1095629,"threshold_uncertainty_score":0.3799693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02251021054144634,"score_gpt":0.2585542541593116,"score_spread":0.2360440436178653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}