{"id":"W4375955948","doi":"10.1186/s12964-023-01123-2","title":"TGF-β1 upregulates secreted protein acidic and rich in cysteine expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome","year":2023,"lang":"en","type":"article","venue":"Cell Communication and Signaling","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Zhengzhou University; First Affiliated Hospital of Zhengzhou University; University of British Columbia; National Natural Science Foundation of China","keywords":"Gene knockdown; Downregulation and upregulation; Transforming growth factor; Ovarian hyperstimulation syndrome; Granulosa cell; Follicular fluid; Andrology; Biology; Follicular phase; Cell biology; Chemistry; Endocrinology; Oocyte; Internal medicine; Cell culture; In vitro fertilisation; Medicine; Gene; Embryo; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001222562,0.0001941237,0.0001656194,0.0002515218,0.0001441281,0.0001721329,0.00007757242,0.0001712313,0.0008715924],"category_scores_gemma":[0.0001017952,0.00007404842,0.0001882779,0.0001639048,0.0002327689,0.00008962394,0.0001278107,0.0002147997,0.0001460336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001557634,"about_ca_system_score_gemma":0.0001327022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002715388,"about_ca_topic_score_gemma":0.000295107,"domain_scores_codex":[0.9999419,0.00001575102,0.000006459641,0.000008356655,0.00001425811,0.00001317608],"domain_scores_gemma":[0.9999502,0.000008007327,0.00002088034,0.000004356482,0.000006385093,0.00001014287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004439889,0.00005667,0.009571851,0.000171858,0.00001659237,0.001009354,0.0001290191,0.00003669926,0.9848509,0.0001081292,0.0001313735,0.003473427],"study_design_scores_gemma":[0.0002130494,0.001952059,0.2585926,0.00006339972,0.0001630005,0.007435797,0.0007014344,0.001631183,0.717894,0.0004379611,0.01089858,0.00001697971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938012,0.004328461,0.000678383,0.0001395758,0.00003270015,0.00004635636,0.0001179945,0.00002735735,0.0008280036],"genre_scores_gemma":[0.9963553,0.002184993,0.0005217223,0.00007767566,0.00002163223,0.0000437814,0.000213967,0.000002658871,0.0005783233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008715924,"threshold_uncertainty_score":0.0029158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02251021054144634,"score_gpt":0.2585542541593116,"score_spread":0.2360440436178653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}