{"id":"W4375956000","doi":"10.1172/jci.insight.170270","title":"Continuous positive airway pressure increases CSF flow and glymphatic transport","year":2023,"lang":"en","type":"article","venue":"JCI Insight","topic":"Cerebrospinal fluid and hydrocephalus","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Center for Advancing Translational Sciences; Yale University; National Institutes of Health; National Cancer Institute; National Center for Complementary and Integrative Health; Raymond and Beverly Sackler Institute for Biological, Physical and Engineering Sciences, Yale University; National Institute of General Medical Sciences; Cure Alzheimer's Fund","keywords":"Glymphatic system; Cerebrospinal fluid; Lymphatic system; Reabsorption; Medicine; Ventilation (architecture); Respiratory system; Anesthesia; Chemistry; Internal medicine; Pathology; Physics; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008026486,0.0001903544,0.0002598526,0.0001182278,0.0002144041,0.00006019204,0.0001670304,0.00007963978,0.0001637981],"category_scores_gemma":[0.0001584603,0.0001642691,0.00006976569,0.0004296953,0.0001413791,0.0002702305,0.00005671076,0.00009961003,0.0002235099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001439735,"about_ca_system_score_gemma":0.00005098838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000136206,"about_ca_topic_score_gemma":0.00002850667,"domain_scores_codex":[0.9986409,0.00006570446,0.0002044542,0.0004644693,0.0002943595,0.000330138],"domain_scores_gemma":[0.9993694,0.0001914419,0.00004576455,0.0002041533,0.00003525009,0.0001539621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007807324,0.0009550145,0.01957108,0.0005411038,0.0001313212,0.002786476,0.009040231,0.0004398335,0.9164819,0.01513037,0.0135166,0.02062532],"study_design_scores_gemma":[0.004760103,0.001467488,0.2255014,0.0003974038,0.0003984575,0.0004776856,0.0002553303,0.02300736,0.6064066,0.002039996,0.1337011,0.001587041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830349,0.0004845786,0.00003563952,0.0003617445,0.0002347453,0.0003186497,0.0001196075,0.000314062,0.01509607],"genre_scores_gemma":[0.9938869,0.0002681494,0.00002415427,0.0008597577,0.0001331113,0.0000233177,0.00001815599,0.00002830731,0.004758073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3100753,"threshold_uncertainty_score":0.6698699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01447022880245433,"score_gpt":0.2380718412430679,"score_spread":0.2236016124406136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}