{"id":"W4376107759","doi":"10.21203/rs.3.rs-2766508/v1","title":"Cognitive impairment in multiple system atrophy and spinocerebellar ataxias","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Beijing Nova Program; National Natural Science Foundation of China","keywords":"Spinocerebellar ataxia; Clinical Dementia Rating; Montreal Cognitive Assessment; Cognition; Atrophy; Rating scale; Neuropsychology; Cognitive impairment; Dementia; Medicine; Memory clinic; Clinical psychology; Audiology; Psychology; Internal medicine; Psychiatry; Disease; Developmental psychology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004085094,0.0004379107,0.0003710901,0.001158547,0.0004178149,0.0004309802,0.0001699863,0.0003210485,0.001941151],"category_scores_gemma":[0.0009771074,0.00009205646,0.0002595608,0.0005910312,0.0002718419,0.0002628461,0.0003850546,0.000276308,0.0002205849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002869684,"about_ca_system_score_gemma":0.0002604557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003203462,"about_ca_topic_score_gemma":0.003075925,"domain_scores_codex":[0.9998324,0.00003786873,0.00002097274,0.00004110227,0.00004095633,0.00002667159],"domain_scores_gemma":[0.999479,0.00009698244,0.0002120535,0.00002012771,0.00007204168,0.0001197521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006265222,0.0001625953,0.9910026,0.00004441244,0.00008246202,0.001324297,0.0002224963,0.00004665943,0.001117598,0.00003499065,0.0001333216,0.005201961],"study_design_scores_gemma":[0.000005897845,0.0001171847,0.9983845,0.000004350325,0.00001849054,0.001121538,0.00008979201,0.000053518,0.00008961894,0.00004248948,0.00007089029,0.000001724361],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988771,0.0003086735,0.00002933681,0.00002429207,0.000004807076,0.000004247796,0.00007597316,0.000002162002,0.0006734778],"genre_scores_gemma":[0.9996179,0.00006288555,0.00004012951,0.00001232207,0.0000103285,0.000002505004,0.0001061831,5.380101e-7,0.0001471035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003203462,"threshold_uncertainty_score":0.006493747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1668362409484641,"score_gpt":0.3968051962484017,"score_spread":0.2299689552999376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}