{"id":"W4376108079","doi":"10.1002/ajmg.a.63237","title":"Persistent chylothorax associated with lymphatic malformation type 6 due to biallelic pathogenic variants in <scp><i>PIEZO1</i></scp>","year":2023,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part A","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"","keywords":"Chylothorax; Medicine; Lymphatic system; Lymphedema; Pathology; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001113116,0.0001632211,0.000619688,0.0003827088,0.00004546902,0.00001338943,0.0001821175,0.0001189357,0.000107873],"category_scores_gemma":[0.001668296,0.0001241035,0.0001286583,0.001555649,0.0001934302,0.00003411061,0.0000526962,0.0003164803,0.0001486887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001176321,"about_ca_system_score_gemma":0.000654939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001034255,"about_ca_topic_score_gemma":0.00002698734,"domain_scores_codex":[0.9975024,0.0002397656,0.0006396914,0.0001817957,0.001042554,0.0003938243],"domain_scores_gemma":[0.9982353,0.0003139275,0.0003776107,0.0001823853,0.0002748798,0.0006159258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0043102,0.004567215,0.1050001,0.000467871,0.0043898,0.01607235,0.03453141,0.01368514,0.05729767,0.0001745824,0.09130068,0.6682031],"study_design_scores_gemma":[0.01474581,0.03948008,0.8438046,0.003246724,0.000808586,0.006420413,0.01710119,0.02262775,0.000473206,0.0001299801,0.05064338,0.0005182961],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958871,0.0002684951,0.0003610909,0.002591392,0.0005009915,0.0001751717,0.000004191619,0.00002749233,0.0001840542],"genre_scores_gemma":[0.9936421,0.001601866,0.0006218635,0.003504358,0.0003201863,0.000007716025,0.0000297386,0.00003069872,0.0002414599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7388045,"threshold_uncertainty_score":0.5060794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02427891230399801,"score_gpt":0.2772605648593011,"score_spread":0.2529816525553031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}